🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Join us! St. Jude is recruiting multiple lab-based faculty at the full, associate and assistant levels in a major expansion of our basic and translational cancer-focused research programs. #cancerresearch #facultyjobs @stjuderesearch stjude.org/cancer-center-…

A potentially safer analog of notoriously toxic amphotericin B has been discovered. This article reviews polyene history, their mechanism of action, and the design of next-gen polyenes that led to a Deerfield-funded biotech. drughunters.com/48B7T5C

I enjoy reading these endeavors to automate & scale-down ligand discovery workflows. If I may offer an opinion: I’d like to see this move beyond Ugi couplings and maintaining the known glutarimide CRBN binder - that’s where the real frontier lies. nature.com/articles/s4146…

We have a 4-year #fundedPhD studentship in organic synthesis available in my lab Newcastle Chemistry in collaboration with AstraZeneca on new synthetic methods to make C-N atropisomeric amides! #PhD findaphd.com/phds/project/p… Deadline = 7th Feb. Informal enquiries welcome. Please RT.

Excited to share that our latest paper has been published in Chemical Communications Kudos to current and former undergrad researchers Muhammad Musozodeh Grace Anderson (she/they), & Joe for their significant contributions! doi.org/10.1039/D3CC04… #sunyoswego #ionicliquids

Years ago when I was a post-doc, my supervisor (Nobel prize) came into the pub with his friend (also Nobel prize). I waved and they walked over, and my supervisor introduced me to his friend not as “my post-doc” but as “my colleague”. What a life lesson to me in so many ways.

Thrilled to share our work illustrating that a small molecule undergoes picosecond dynamics in its bound state with an intrinsically disordered protein, now out in J. Am. Chem. Soc.. 🍝💊🧲D. Flemming Hansen vaibhav shukla Angelo M Figueiredo UCL Faculty of Life Sciences #NMRchat (1/4) pubs.acs.org/doi/10.1021/ja…

There's still time to apply for the inaugural class of SPARK Scholars! x.com/DamonRunyon/st…

We have a 1-year postdoc in organic synthesis available at our sister lab in Siena, Italy, working on merocyanine photoacidic systems for solar energy harvesting in collab with Cristian Pezzato. Please share widely, and contact me directly if interested! unisi.it/albo_pretorio/…

A Meeting Report highlights the latest research that convened at the 2023 Bringing Chemistry to Medicine symposium at St. Jude Children's Research Hospital focused on targeting dysfunctional gene regulation and other 'undruggable' processes rdcu.be/dE25H

A small molecule FeM-1269 minimally aggregates and dose-dependently mobilizes iron across lipid bilayers even at high concentrations, showing potential in treating iron transporter deficiencies rdcu.be/dGaFY

Reflecting on the amazing #AAI2024: So grateful to The American Association of Immunologists (AAI) for recognizing our discoveries of innate immune sensors and PANoptosis. A big thank you to my current & previous lab members for their dedication that has led to these discoveries. Kanneganti Lab St. Jude Research

Rapid automated iterative small-molecule synthesis nature.com/articles/s4416…

It is hard to beat nature in the design of antibiotics. In this review, we analyze the sophisticated mechanisms of many antibiotic substances with an eye toward future antibacterial drug discovery. nature.com/articles/s4158…

We’re happy to announce that the Sandford Lab is moving to UTSAChemistry in January 2025! We are also hiring postdocs to start in early 2025, including on our new NIH @NIGMS MIRA award(!), more details below 1/3

Excited to share our study in Cell on expanding the druggability of GTPases beyond K-Ras and start putting the entire family (150+ proteins) on the map of drug discovery! Kevan Shokat UC San Francisco UCSF Helen Diller Family Comprehensive Cancer Ctr HHMI (1/7) cell.com/cell/fulltext/…

I am deeply honored to receive the 2025 Kazuhiko Kinosita Award in Single-Molecule Biophysics from the Biophysical Society. Our achievements build on the foundations laid by many great scientists, including all past recipients of this award. I would like to extend my sincere

We are very pleased to be recruiting for academics to join Bristol Chemistry. If you are passionate about your research and love teaching please apply: bristol.ac.uk/jobs/find/deta…

Researchers have transformed small molecule synthesis, reducing reaction analysis from minutes to milliseconds and transforming a key bottleneck in high-throughput drug discovery. ow.ly/Ib8J50UpcvF