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🧵1/9 Excited to share our latest research on human microglia! We explored microglial heterogeneity through single-cell RNA sequencing of 215,680 live human microglia from 74 donors across neurological diseases. #NeuroImmunology #Microglia Nature Neuroscience nature.com/articles/s4159…

Pre-print alert! 🎉 In this collaborative project we linked microglial states to lesion expansion and repair in multiple sclerosis human brain tissue, using spatial transcriptomics analysis. Thanks to everybody who contributed! Read about it here: biorxiv.org/content/10.110…

Super excited to share my PhD work, out now in nature. Here, myself, Lydia Lynch, and all my wonderful co-authors explored the link between circadian rhythms, energy homeostasis and innate T cell function. A thread: 🧵 nature.com/articles/s4158…

Makes me wonder about the DNA Methylation clock analyses usually performed on blood cells as representatives for the whole body aging... While it may reflect only the immune system...

Yesterday during a lab meeting, my mentor informed me that I may no longer progress in my career due to my so-called 'infamy.' I was told that I was to blame for the challenges I've been facing in publishing my work—that my 'negative' political activism might be provoking the

Microglia are key players in neurodevelopment. It is thus essential to include them in brain organoids to study neurodevelopment, especially to study prenatal immune activation and how it impacts such a delicate process.

Thrilled to share our latest work on how #SHIP1, a gene linked to #neurodegeneration, affects #microglia in early #brain development. Congrats to Alessandro Matera, Compagnion Anne-Claire and the many #collaborators Immunity Faculté de biologie et de médecine (inactif) sciencedirect.com/science/articl…

Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses nature.com/articles/s4159…

Very excited to share our new work, now on bioRxiv, on specificity of memory in human macrophages biorxiv.org/content/10.110… (1/8)

*Every single* cure for a disease ultimately flowed from basic exploratory research. Stopping basic research is like stopping the mountain rains and expecting rivers of cures to still flow. Examples: 1) studying saliva of Gila monster -> GLP1's 2) studying funghi -> first

Last night my brilliant friend with 20 years of expertise in Neuroscience including a decade at NIDA was fired because she was recently promoted for her outstanding performance and it triggered the probation period. This is not making NIH more efficient, this is not making us

Time indeed to get scientists on the ground in front of TV cameras. The public needs to hear from us—how we drive medical breakthroughs, train future leaders, and fuel the economy. #FundScience

In our latest study, led by amazing Jack Humphrey we present a long-read RNA sequencing atlas of human #microglia isoforms! We found novel Isoforms involved in microglial immune responses and their association with #Alzheimer and #Parkinsons risk loci. bit.ly/4hvNuTT

A BIG STUDY in Nature Medicine: Which food makes you age faster? Scientists looked at 105,000 people in 30 years. The statistics is impressive. The study is open-access, so everyone can read it. 📍 Findings: The diet that ROCKS: fruits, vegetables, whole grains, unsaturated

The reality gap “Our brains do not just passively perceive the world—they construct it. Research shows that imagined and real experiences can produce strikingly similar neural activity, raising deep questions about the nature of reality itself.” #reality iai.tv/articles/the-r…

Maternal immune activation may compromise offspring #neurodevelopment via #glia activation. In this chapter, we discuss evidence and mechanisms gathered via #COVID_19 , animal and brain-organoid models. Alice Buonfiglioli, PhD Dilansu Güneykaya Bilge Ugursu shorturl.at/0B8Bw

Proud to share our latest Cell paper. We present a novel immune population termed PNS microglia that regulate neuronal soma size throughout evolution. cell.com/cell/abstract/… #Microglia#PNS#NeuronalSomaSize#Macrophage#BodySize#Neuroimmunology#Evolution (1/8)

The first textbook on quantum biology is now freely available on the arXiv! Dr. Nathan Babcock has made the entire field freely accessible, and plans to keep the link updated after constructive conversations across disciplines at the Quantum Biology GRC arxiv.org/abs/2503.11747

Hope is not naive when you have a vision and a movement behind it. Hope is in fact righteous. This is the dawn of a new era in New York City. And we will win it together.