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6 years later, and I’m upgraded to Dr. Darwin Kwok Ph.D.! 🎓🥼 Thank you to the 60+ family, friends, and colleagues who listened in to my dissertation. You all made this journey full of unforgettable memories and pure unadulterated joy. It was truly a blast. 🚀#ucsf #phdfinished

Maximum 15% plagiarism is a new one.

1/ JUST IN: an 8 year #kidneycancer journey now published in nature: “A personalized neoantigen vaccine generates anti-tumor immunity in high-risk renal cell carcinoma”. A trial of #RCC vaccine, led together with first author David Braun Yale Cancer Center and #PatrickOtt #DerinKeskin

Peptides from abnormal RNA processing in cancer offer an immunotherapy target nature Darwin Kwok nature.com/articles/s4158… nature.com/articles/d4158…

New in nature, researchers led by Okada Lab @ UCSF, Joe Costello, and Klebanoff_Lab show that in various cancers, including #glioma, alternative RNA splicing generates tumor-specific antigens. The findings present new targets for #immunotherapy: nature.com/articles/s4158…

It was such a wonderful experience to collaborate with such talented individuals in the Klebanoff_Lab! To many more team-up opportunities in the future 🥂🎉 #mskcc #collab #teamscience

Nature research paper: Tumour-wide RNA splicing aberrations generate actionable public neoantigens go.nature.com/4hQCOjk

Personalized Therapies Targeting Neoantigens: Catherine Wu, Alena Gros, and Christopher A. Klebanoff addressed this topic in a symposium at the inaugural AACR IO Conference on Discovery and Innovation in Cancer Immunology. #AACRIO25 Klebanoff_Lab

.Cancer Immunology Research editor-in-chief Philip D. Greenberg, Kole Roybal, and Christine E. Brown discuss "CAR T Cells for Solid Tumors" in a symposium at the AACR IO Conference on Discovery and Innovation in Cancer Immunology. #AACRIO25 Kole Roybal

Tumor-wide immunotherapy targets identified in new study New PICI-funded research in nature identifies a novel class of RNA splicing-derived public neoantigens—tumor-wide targets that could make T cell therapy more effective and broadly applicable. PICI Investigators at UC San Francisco

Thank you, OncoDaily IO, for the feature! Looking forward to another brilliant year of groundbreaking therapies and innovations in immuno-oncology! #CancerResearch #Neoantigens #Tcelltherapy #Immunology

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“It is hard to put into words the extent of the damage being done to the US research enterprise, which is of almost incalculable value to both the nation itself and the wider world… An assault on science and scientists anywhere is an assault on science and scientists

Excited to have our paper featured on the front page of ACIR! Check out their excellent review and illustrations! Tumoral RNA splicing: source of neoantigens for off-the-shelf therapies? acir.org/weekly-digests… #immunotherapy #tumorwidesplicing #neoantigens UCSF Neurosurgery

In a recent study on Cancer Cell, Platten lab (DKFZ) highlights the pivotal role of MHCII-restricted antigen presentation by tumor-infiltrating blood-borne myeloid cells (BBMs) in maintaining CD8+ T cell functionality within brain tumors. MHCII-restricted antigen presentation

Stem-like T cell populations have significant therapeutic potential and are crucial for vaccine efficacy. Joanna Groom explored ways to optimize the formation of stem-like memory T cells (TSCM).bit.ly/43MKnUb WEHI (Walter and Eliza Hall Institute) #KSCancerImmune25

Bravo Mike V. Gormally, MD PhD 🙌! Memorial Sloan Kettering Cancer Center MSK Department of Medicine #Tcellpower

🚨Today in Cell, we show that RNA splicing factor mutations in myeloid cancers generate splicing-derived public neoantigens targetable by #TCR tx. Amazing collaboration co-led by Abdel-Wahab Lab, Robert K. Bradley, and Klebanoff_Lab. #Tcellpower cell.com/cell/fulltext/…

Another incredible piece from the giants in cancer-specific splicing! Omar and his team’s research motivated my PhD thesis and continues to inspire me to this day. Check out this monumental work on the discovery of splicing-derived neoantigens in liquid tumors! 🚀🚨