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Check out our new preprint on the after-life of intestinal cells: biorxiv.org/content/10.110…. Cells that are shed each day from our gut are thought to die immediately upon their dissociation from the tissue. Here we show that this is not the case (1/6).

Our ADAR-based RNA sensors just came online! rdcu.be/cWX7o It allows you to express protein payloads in live cells in direct response to the presence of specific RNA transcripts. Also Eerik Kaseniit, welcome to twitter.

What if you could image 🔬cells and then choose which ones to sequence 🧬? What if you could go back and image 🔬cells that you previously sequenced 🧬? Now you can 🔬 then 🧬 then 🔬 cells again with Light-Seq! nature.com/articles/s4159… Let’s dig in 🧵.

New paper! It’s absolutely wild what you see when studying bacteria using single-cell RNA-Seq! Unlike in eukaryotes, we found a genome-scale pattern of correlations among genes showing a strong dependency on global chromosomal locations. biorxiv.org/content/10.110… Andrew Pountain

I am really excited to share that our new pre-print on “A machine vision guided robot for fully automated embryonic microinjection” is out. Thanks to Andrew Alegria, all collaborators and Suhasa Daryl Gohl

🚨 New pre-print alert!🚨 Led by the brilliant, twitter-less post-doc James Hope. We built a 🤖 exoskeleton for 🐭🐁 so we can study their 🧠's as they go around navigating their world. An e.g., imaging 1000s of neurons in the cortex when mice walk an 8-maze. A 🧵

On the cover of the April issue of GENETICS: An automated microinjection of Drosophila embryos by a computer vision-guided robot. Alegria et al. present a machine vision guided generalized robot that automates the process of microinjection in fruit fly and zebrafish embryos. 🧵⬇️

New paper in our lab led by Andrew Alegria and Amey Joshi published in Genetics Society of America . Fun collab with Daryl Gohl and Bischof group @umnme College of Sci & Eng We also made it to the cover! academic.oup.com/genetics/artic…

READ: “High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot.” Alegria et al. U.S. National Science Foundation (ORIP support through 1R21OD028214, 1R24OD028444) academic.oup.com/genetics/artic…