Aspirin, cardiovascular events, and major bleeding in older adults: extended follow-up of the ASPREE trial: European Society of Cardiology Journals 🥸Aspirin for primary prevention for older pts = MACE! 👇👇👇👇

The new AHA/ACC/Multisociety #ClinicalGuideline on high blood pressure provides updated recommendations for clinicians on the prevention, detection, evaluation, and management of high blood pressure in adults. Get the details: jacc.org/doi/10.1016/j.… #Hypertension #JACC

Cardiologists: marked safe from being replaced by AI today ✅

First-Line β-Blocker Use for Hypertension in the Veterans Health Administration JAMA jamanetwork.com/journals/jaman…

Dr Joseph McCollom DO Dr Leo Alex S. Aguirre, MD Michael Angarone Juan M. Masini Bob Mackey, The Bow Tie Education Guy Ak Sedai 🌟 Stephen David Beck Joe Thomas, MD, FHM Amar Kelkar, MD, MPH, FACP First #BowTieFriday in a while for me today!

Staggering numbers by the Lancet. Vaccinations have: - Averted 154 million deaths - For every death averted, 66 years of full health were gained on average = 10.2 billion years total - Accounted for 40% of the observed decline in global infant mortality

We Are Watching a Scientific Superpower Destroy Itself The New York Times nytimes.com/2025/09/08/opi…

Delighted to share our latest study on a nanobody-based sensor of GPCR activation and signaling! A genetically encoded nanobody sensor reveals conformational diversity in β-arrestins orchestrated by distinct seven transmembrane receptors | PNAS pnas.org/doi/10.1073/pn…

Happy #BowTieFriday

I Run the F.D.A. Pharma Ads Are Hurting Americans The New York Times nytimes.com/2025/09/13/opi…

There’s a name for a diagnostic test that’s 42% sensitive and 83% specific: useless.

The largest cancer hospital in the world, MD Anderson Cancer Center now mandates face masks from October - March.

I fear the public will never truly realize the immense damage done to our scientific research system and its consequences. A loss of ~$4.5 billion in frozen or cancelled grants with at least 148 impacted clinical trials = 138,000 patients due to be enrolled or already enrolled.

Research output after tenure drops off a cliff for business, economics, sociology, and other non-lab fields. But it remains high post-tenure in lab-based fields such as chemistry, physics, computer science, and engineering.

Age of Nobel Physics Laureates (1901-2025)

Fred Ramsdell, one of three who who received the Nobel Prize for Physiology or Medicine yesterday for work on immunology, hasn't been informed of his win: he's "off the grid" hiking, and can't be contacted. theguardian.com/science/2025/o…

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

"Cuts to training grants and other NIH programs are having a chilling effect on researchers, leading to a 'lost generation.'" ⁦STAT⁩ statnews.com/2025/10/16/for…