
David Eisner
@davidaeisner
@TheBHF Professor of Cardiac Physiology @OfficialUoM. Editor-in-Chief @JGenPhysiol. I research calcium signalling in the heart. (All views my own).
ID: 954320945010872321
19-01-2018 11:53:38
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1,1K Followers
475 Following


AlphaFold predictions for GrTX-SIA binding to human Naᵥ1.6. Rita Collaço, Filip Van Petegem and Frank Bosmans UGent Geneeskunde & Gezondheidswetenschappen show that ω-Grammotoxin-SIA inhibits voltage-gated Na⁺ channel currents. hubs.la/Q02HM_m40 #IonChannels #VoltageGatedNaChannels


.Man et al. Glasscock Lab SMU Biology (hubs.la/Q02KqvnL0) reveal that, thought they only generate small currents in the sinoatrial node, Kv1.1 channels have a significant impact on cardiac pacemaking. Learn more in Research News: hubs.la/Q02KqCWh0



Caldwell et al found atrial #ttubules can be restored post #HF, improving Ca handling & heart function. Learn about therapeutic insights for #atrial dysfunction in HF ahajrnls.org/3B7FeK7 Jessica Caldwell Katharine Dibb David Eisner Andrew Trafford Callum Quinn GMadders


Great news! Congrats Jessica Caldwell. Also, Jess is on the job market and will be a great colleague. Plus her science is 🔥






Liu and Bezanilla The University of Chicago describe a voltage-gated sodium channel mutant that removes fast inactivation while the fast inactivation particle, the IFM motif, remains bound, indicating that fast inactivation requires additional conformational changes hubs.la/Q02ZJkSP0




The University of Manchester O-Fish-ial Lab Read the full article in #PhysiologyNews: buff.ly/41IWSz4 🧵8/8

Great to publish this in Journal of General Physiology

Great to publish in Journal of General Physiology

Great to publish in Journal of General Physiology

