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In our study in Science Advances, we reveal how ssDNA binding activates transcription factor PafBC, triggering the DNA damage response in #Mycobacteria. Read more: science.org/doi/10.1126/sc… 🔬 Cryo-EM structure 🧬 ssDNA-WYL domain interaction

Measles outbreak erupts in one of Texas’ least vaccinated counties dlvr.it/THrtv4

No more clicking around—your DNA sequences now appear directly in your results email. See if your experiment worked straight from your inbox 📧

Health Secretary RFK Jr responding to the first deaths from the measles outbreak in Texas

2 measles deaths in the US now. Measles cases popping up all over the country. Utah banned fluoride today—though 75 years of data show it prevents tooth decay. RFK Jr is touting cod liver oil and “nutrition” as cures for the most contagious human disease. 1/

The peer-revied version of our paper on the structure of the Nipah virus RNA polymerase in complex with RNA is out in Nature Communications. Congratulations to first-author Fernanda Sala and many thanks to the reviewers for their comments! nature.com/articles/s4146…

Online today at Nature Communications: in a major team effort, we reveal the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator γ-TuRC: nature.com/articles/s4146…

Excited to be giving this webinar soon. Hope to see you then!

Molecular machines enable efficient energy production in mitochondria. Using cryo-electron tomography Ben Engel and Florent Waltz have gained insight into the architecture of mitochondria at unprecedented resolution. Science Magazine Swiss National Science Foundation ow.ly/irOA50Vm1xK

Our work on HIV-1 matrix, led by James Stacey and Dominik Hrebik Dominik Hrebik, is in this week's nature. Extended explanatory video from Margot Riggi. nature.com/articles/s4158…

Tune in Wednesday for my webinar on antiviral antibody sequencing and epitope mapping by mass spec and EM.

Happy to share an update to FollowRelionGracefully! Real-time previews & stats plotting for most #cryoEM #Relion jobs (incl. #teamtomo). Faster, more modular code, uniform UI, & selection. Feedback welcome! github.com/dzyla/Follow_R…

Please RT. Post-doc opportunity alert! 💥 closing 5th May.. Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust. For more details and to apply please see imperial.ac.uk/jobs/search-jo…

Simultaneous polyclonal antibody sequencing and epitope mapping by cryoEM and mass spec: how far can we go? Check out the final version of our paper in eLife: elifesciences.org/articles/101322

I’m experiencing repeated errors during tomography data acquisition. Any suggestions on how to resolve this issue? Thanks in advance.

We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena Vazquez-Sarandeses, Vasya Vasilii Mikirtumov Jeff Noel&Oli Daumke biorxiv.org/content/10.110…

Excited to present CryoBoltz ❄️⚡, a multiscale guidance approach for steering AlphaFold3/Boltz-1 to sample structures that are consistent with experimental cryo-EM density maps. 🧵1/7 arxiv.org/abs/2506.04490 Joint work with Axel Levy Gordon Wetzstein & Ellen Zhong!