De Biasio Lab
@de_biasio_group
We're a lab based at @KAUST_news using Cryo-EM to study DNA replication and repair complexes.
ID: 1781959473638105089
https://cryoem.kaust.edu.sa/ 21-04-2024 08:13:56
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Check out our latest preprint! We use #CryoEM continuous heterogeneity analysis to model how ATP-hydrolysis triggers structural changes in an AAA+ helicase that drive DNA unwinding – a fundamental step in replication! biorxiv.org/content/10.110… #CryoEM #DNAReplication Structura Biotechnology
Check out the latest preprint from the De Biasio Lab using Cryo-EM and modeling to capture the dynamics of DNA unwinding for replication.
A remarkable paper from the laboratory of the De Biasio Lab, using state-of-the-art CryoEM tools to experimentally visualize the detailed atomic movements underpinning DNA unwinding by a replicative helicase!
De Biasio Lab Structura Biotechnology A remarkable paper from the laboratory of Alfredo De Biasio, using state-of-the-art CryoEM tools to experimentally visualize the detailed atomic movements underpinning DNA unwinding by a replicative helicase!
A remarkable paper from the laboratory of the De Biasio Lab, using state-of-the-art CryoEM tools to experimentally visualize the detailed atomic movements underpinning DNA unwinding by a replicative helicase! #helicases #cryoEM #DNADay
Here is our latest paper together with Raphael Guerois on the MCM8-9 helicase complex and its activation by HROB. Congratulations to Ananya Acharya and many thanks to Alberto Ciccia and Ralf Seidel labs nature.com/articles/s4146…
We're thrilled to announce our new preprint on the structure of the human alternative clamp loader, CTF18, bound to PCNA. A big shoutout to our star PhD student Giusy Briola for spearheading this work! biorxiv.org/content/10.110… #DNAReplication
We celebrate our star PhD student, Giusy Briola, who successfully defended her thesis on the ‘Structure of the human alternative clamp loader CTF18-RFC bound to PCNA.’ We wish her continued success in her future endeavors.
