Declan (@declanfj) 's Twitter Profile
Declan

@declanfj

Pancreatic surgeon and prehabilitation fanatic.

ID: 3425850137

calendar_today16-08-2015 13:13:36

3,3K Tweet

1,1K Followers

924 Following

Giovanni Marchegiani (@gio_marchegiani) 's Twitter Profile Photo

🚨 From ASCO 2025 👉 Preop chemo with PAXG 🆚 mFOLFIRINOX for extending event-free survival (EFS) in resectable or BR PDAC (phase 3 CASSANDRA trial) 🆙 PAXG 3-year EFS 31% vs. 13% P = .003 🫸 Immature analysis for survival but.. future practice changing?! 🧐

🚨 From <a href="/ASCO/">ASCO</a> 2025 

👉 Preop chemo with PAXG 🆚 mFOLFIRINOX for extending event-free survival (EFS) in resectable or BR PDAC (phase 3 CASSANDRA trial)

🆙 PAXG 3-year EFS 31% vs. 13% P = .003

🫸 Immature analysis for survival but.. future practice changing?! 🧐
Zhi Ven Fong, MD MPH DrPH (@zhivenfongmd) 's Twitter Profile Photo

If you’re a GI/HPB surgeon/oncologist who couldn’t make it to ASCO 2025 & trying to scour for its ongoings online like I have been, here’s the 2 trials you’d probably be interested in with a concise breakdown: MATTERHORN, & CASSANDRA! (Also tagging ppl who are smarter than me)

If you’re a GI/HPB surgeon/oncologist who couldn’t make it to <a href="/ASCO/">ASCO</a> 2025 &amp; trying to scour for its ongoings online like I have been, here’s the 2 trials you’d probably be interested in with a concise breakdown:

MATTERHORN, &amp; CASSANDRA!

(Also tagging ppl who are smarter than me)
Allison Betof Warner, MD, PhD (@drbetofmdphd) 's Twitter Profile Photo

I’ve been in the exercise oncology field for 20 years and for all of that time, the main criticism has been “show me a well controlled RCT.” Well, here it is. Exercise following adjuvant chemotherapy for colon cancer reduced recurrence and improves OVERALL SURVIVAL! #ASCO25

Matthew Martin, MD, FACS, McRIB (@docmartin22) 's Twitter Profile Photo

Big win for robotic approach in this study of rectal cancer resections: Robotic vs Laparoscopic Surgery for Middle and Low Rectal Cancer jamanetwork.com/journals/jama/…

Joe Walsh (@walsh_joe) 's Twitter Profile Photo

As a Doctor I am held to a standard where “if I didn’t document it, it never happened” Why is the GMC any different? If something went wrong with a patient under my care, and my documentation was non-existent, how would the GMC treat me?

Royal Surrey (@royalsurrey) 's Twitter Profile Photo

First-of-a-kind pilot study from Royal Surrey and University of Surrey finds that exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumours. Read the full article: royalsurrey.nhs.uk/news/exercise-…

First-of-a-kind pilot study from Royal Surrey and <a href="/UniOfSurrey/">University of Surrey</a> finds that exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumours.

Read the full article: royalsurrey.nhs.uk/news/exercise-…
Vincent Groot (@vincgroot) 's Twitter Profile Photo

🚨 New in Annals of Surgery showing ⬆️ survival with routine imaging vs symptomatic follow-up after #pdac resection. 🕵🏼‍♂️Routine imaging also associated with asymptomatic recurrence and recurrence treatment. DPCG Marc Besselink Giovanni Marchegiani journals.lww.com/annalsofsurger…

🚨 New in <a href="/AnnalsofSurgery/">Annals of Surgery</a> showing ⬆️ survival with routine imaging vs symptomatic follow-up after #pdac resection.

🕵🏼‍♂️Routine imaging also associated with asymptomatic recurrence and recurrence treatment.

<a href="/DPCG_official/">DPCG</a>
<a href="/MarcBesselink/">Marc Besselink</a> 
<a href="/Gio_Marchegiani/">Giovanni Marchegiani</a> 

journals.lww.com/annalsofsurger…
IHPBA (@ihpba) 's Twitter Profile Photo

➡️HPB Journal Highlight 📉 Cullinane et al. found no benefit of somatostatin analogues in preventing postoperative pancreatic fistula after pancreatic surgery (meta-analysis, 6947 pts). Routine use not recommended! 🚫🩺 🔗tinyurl.com/3chcjf8j #PancreaticSurgery

➡️HPB Journal Highlight 📉 Cullinane et al. found no benefit of somatostatin analogues in preventing postoperative pancreatic fistula after pancreatic surgery (meta-analysis, 6947 pts). Routine use not recommended! 🚫🩺 
🔗tinyurl.com/3chcjf8j 
#PancreaticSurgery
BJS Academy (@bjsacademy) 's Twitter Profile Photo

Preoperative management and resectability criteria in perihilar cholangiocarcinoma ➡️ bjsacademy.com/bjs-academy/yo… 🗨️ Treatment often considered futile, but a thorough work-up, and surgery for selected patients is worthwhile. -Jonothan Earnshaw #Surgery #HPB Kjetil Søreide

Preoperative management and resectability criteria in perihilar cholangiocarcinoma
➡️ bjsacademy.com/bjs-academy/yo…

🗨️ Treatment often considered futile, but a thorough work-up, and surgery for selected patients is worthwhile. -Jonothan Earnshaw

#Surgery #HPB <a href="/ksoreide/">Kjetil Søreide</a>
RAPID-I Trial (@rapidi_trial) 's Twitter Profile Photo

An update from RAPID-I on recruitment: End of June target - 113 Actual recruitment - 115 Let's keep it going! #pancreatitis #clinicalresearch #clinicaltrial

Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

Exercizumab is real. Aerobic exercise cut colon cancer recurrence + death. It’s time to combine movement with medicine not one or the other. #oncology #Cancer NEJM OncoAlert ASCO #ASCO25 DOI: 10.1056/NEJMoa2502760

Exercizumab is real.
Aerobic exercise cut colon cancer recurrence + death.
It’s time to combine movement with medicine  not one or the other.
#oncology #Cancer <a href="/NEJM/">NEJM</a> <a href="/OncoAlert/">OncoAlert</a> <a href="/ASCO/">ASCO</a> #ASCO25 
DOI: 10.1056/NEJMoa2502760
Martyn Stott (@mstotty88) 's Twitter Profile Photo

What does new onset diabetes mean in surgery for pancreatic cancer? ✅It’s unique to PDAC - it’s rare in other neoplastic HPB processes like ampullary or distal CCA. 🧐Its under diagnosed - it must be screened for or it won’t be identified. 🤢It increases the risk of DGE. 😁It

Shivan Sivakumar (@shivansivakumar) 's Twitter Profile Photo

Hi all, we have funding for two resident doctors- post fy2-st6 to a Hpb medical oncology clinical research fellowship in Birmingham. They would do our clinical trials clinic, a standard of care clinic and have two research days a week. Please let any suitable trainees know.