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Grateful for an inspiring lecture from the incomparable Carolyn Bertozzi at #NOS2023ND!

Way to go Avraz Anwar and mike !

Check our latest pub describing stabilized PUM analogues. Congrats to Avraz Anwar, Chris, and Michael Garza; and our collaborators in the Richard H. Ebright lab! doi.org/10.1002/cmdc.2…

Excited to share our story on cross-beta epitope mimics targeting tau propagation, out now in J. Am. Chem. Soc.. Grateful to all involved on this project, and a special congrats to first author Ben Rajewski!! pubs.acs.org/doi/10.1021/ja…

Almost the end of #AusPeptide2023 sadly! Thank you all for coming and having a great time, giving amazing presentations and presenting fantastic posters. Hope to see everyone again soon! 🇦🇺👀🧪

Hats off to Theo and Natalia, who passed their candidacy exams this month!👏🎉 Cake, coats, and congrats on job well done!!

Had an amazing time at the Purdue University Notre Dame Symposium (PUNDS). There were so many great talks/research being done from each university. With that being said, I am honored to receive the Best Presentation Award for my talk!

4 new group members this month! Thrilled to welcome postdoc Abha Dangi, and 1st year grad students Ana-Teresa Mendoza, Alexandre Renon, and Fadwa Kamari. Welcome to the team!

#OnTheCover Stabilizing Pseudouridimycin: Synthesis, RNA Polymerase Inhibitory Activity, and Antibacterial Activity of Dipeptide-Modified Analogues (ChemMedChem 1/2024) (J. R. Del Valle et al.) Del Valle Lab onlinelibrary.wiley.com/doi/10.1002/cm…

Congrats to Isaac Angera for taking home a 2nd place poster award at the 2024 Peptides GRC!! Well-deserved! Stay tuned for more on his exciting foray into "mini-tau" macrocycles.

At last... we're thrilled to send our story on macrocyclic mini-tau seeds out into the world. Organic chem, protein mimicry, cryo-EM, cell function; something for everyone! Congrats to Isaac & Xueyong, and collabs from Purdue and IUSM! chemrxiv.org/engage/chemrxi…

Huge week for 5th year ⁦⁦Ben Rajewski⁩. Thesis defense, Dow outstanding grad student award, and birthday to boot! Congrats Ben! 🥂

New Acc. Chem. Res. from the lab dropped online yesterday: pubs.acs.org/doi/10.1021/ac…. Right on first author Isaac's birthday, and one day before second author Madi's birthday. Practically twinsies! Happy bday guys! 🎂

Last week the lab got together to bid farewell to Ben Rajewski aka Dr. "beta-bracelet". Congrats, Ben, and all the best in Chicago!

Congrats to Avraz Anwar, whose total synthesis of marformycins A&D appeared in in J Org Chem/Org Lett! Special thanks to Yassin and collaborators in the Richard H. Ebright lab. doi.org/10.1021/acs.or…

Our paper on delta-heteroatom proline surrogates in collagen is now online. Congrats to Taylor, Madi, and Natalia! pubs.rsc.org/en/content/art…

The fun with unnatural proline surroagtes continues... Check out our paper on stabilized aPP proteomimetics. Congrats to first author Madison Wright and special thanks to collaborators in the Horne and Smith labs! nature.com/articles/s4200…

RSC Chemical Biology paper in collaboration with the Stahelin just accepted! Stapled peptides targeting the dimer interface of the Ebola virus VP40 matrix protein. Congrats to Madi, Roopashi, and collaborators in the Stahelin and Chapagain labs! doi.org/10.1039/D5CB00…

Check out this Just Accepted paper from Avraz Anwar describing a streamlined synthesis of N-amino peptides. This general protocol will vastly accelerate studies on amide-to-hydrazide replacement in peptides. Congrats, Avraz! doi.org/10.1021/acs.jo…