Come and watch this! My PhD work is featured! 🎉

📢 4th Edition of Royal Society of Chemistry Nucleic Acids in Chemistry and Biology has now been released (Blackburn/Gait/Egli/Jon Watts) – The bible for scientists who work with nucleic acids Furthermore, I wrote the revamped chapter on DNA and RNA Sequencing! 🥳 rsc.li/3OyMtNa

Preparing for a conference presentation with the smallest ironing board ever to iron the fabric poster 🎉

My poster is now up at the #Biochemistry2022 conference in Münster! Come have a look and chat to me (in 🇩🇪 or 🇬🇧) about blue-light controllable DNA, done under supervision of Michael Booth as part of SBM CDT. It is nice to have in person events again! 🎉

We’ve engineered light-activated communication between synthetic cells and living cells! 🧬⚡️🧫 Check out our preprint, led by my amazing student Jefferson Smith Dr Denis Hartmann SynBio CDT Oxford Chemistry UCL Chemistry Synthetic Cell initiative Build-a-Cell biorxiv.org/content/10.110…

If you are curious what I spent a large part of my DPhil on so far, my project on blue light-activatable DNA is now available on ChemRXiv as a preprint! 🎉 SBM CDT Oxford Chemistry

One of my DPhil projects with Michael Booth is now on chemRxiv! We developed light-activated antisense oligonucleotides by photocaging the backbone and could use that to control gene knockdown in cell-free expression! Have a look below! SBM CDT Oxford Chemistry

Engineering and Physical Sciences Research Council We've got *2* EPSRC PhD opportunities to join our group in London to study the chemistry and application of nucleic acids, photocages, and polymers! 😍🧬🔦🌡️🧪 x.com/DrMikeBooth/st…

.Michael Booth, Dr Denis Hartmann and co. report photocaged antisense oligonucleotides to knockdown cell-free protein synthesis using light. UCL Chemistry Oxford Chemistry SBM CDT UCL Chemistry and Light nature.com/articles/s4200…

We’ve developed light-activated antisense oligonucleotides by conjugating photocages to phosphorothioates 🤩🧬🔦! Published in Communications Chemistry, led by Dr Denis Hartmann Oxford Chemistry SBM CDT UCL Chemistry #ASO #DNA #light nature.com/articles/s4200…

Great work by our very own Dr Denis Hartmann out now in Communications Chemistry! x.com/DrMikeBooth/st…

We've topologically constrained antisense oligonucleotides into a handcuff structure, via photocages, to control gene knockdown! Published in Chemical Communications, led by Dr Denis Hartmann Oxford Chemistry SBM CDT UCL Chemistry #supramolecular #ASO rsc.li/3zY0vC5

We made *orthogonally* light-activated antisense oligonucleotides as precise switches for cell-free systems 🔦🧬 Published in J. Am. Chem. Soc. 🤩! Led by Giacomo Mazzotti Dr Denis Hartmann Oxford Chemistry SBM CDT UCL Chemistry #DNA bit.ly/3AlvQyO

And this is my last paper from my PhD published! 🎉

Two of my PhD papers are now published back-to-back in J. Am. Chem. Soc.! I really enjoyed working on those two projects, do go and give them a read 😁

My PhD work has made it into Synthetic Cell initiative 🥳

Starting off our second day with Dr Denis Hartmann from Timothy A. Barendt talking about PDI macrocycles for molecular electronics and host-guest chemistry! #ECRMASC2024

My first major piece of postdoc work in TAB Lab is finally out in Angewandte Chemie. 🎉

A Bis-Perylene Diimide Macrocycle Chiroptical Switch (Timothy A. Barendt and co-workers) Dr Denis Hartmann TAB Lab UoBChemistry Martijn Zwijnenburg #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…

More of my postdoc work has now been published in Chemistry Europe. This was a super fun project to work on, and with lots of diverse and challenging synthesis, characterisation, crystallography and DFT!