🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Not long left to apply for postdoc positions on 🧬 replication in my new lab MRC_HGU Institute of Genetics and Cancer. A range of projects available, some of them related to nature.com/articles/s4158…. Informal enquiries welcome. elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

A great opportunity for anyone looking for an exciting post-doctoral position!

Thrilled to announce another preprint from our lab! Dr. Lillian found that RTEL1 and MCM10 help replication forks overcome topological stress during termination. Thanks also to Brandt Eichman Darren Heintzman Tata Kavlashvili

Really excited to share the methods chapter we wrote for DNA Damage Responses as a part of Methods in Molecular Biology series. Here we describe really fun assays to monitor DNA replication termination using 🐸🥚 extracts! #gelsnotcells ⁦Dewar Lab⁩ link.springer.com/protocol/10.10…

Excited to share our latest paper, just published in EMBO J: embopress.org/doi/abs/10.152… We found that topoisomerase II poisons exert different and unexpected effects on DNA replication. Congrats Sabrina X. Van Ravenstein! Thanks also to our collaborators Osheroff Lab and David Cortez

📢 Hot off the press 📢 🧬 Ever wonder why some DNA sequences are difficult to replicate? Using reconstituted replisomes we revealed that structure-forming repeats induce robust replication stalling and uncovered structure-specific recovery mechanisms: nature.com/articles/s4146…

The Department of Biochemistry Vanderbilt Biochemistry in Vanderbilt Basic Sciences Vanderbilt School of Medicine Basic Sciences is recruiting new faculty! Apply here: apply.interfolio.com/112443

Wish my labmates had warned me.. would have cleaned up my bench. #PhDone

Our new cryo-EM structure explains how the MRN complex can act both as DNA double-strand break sensor & DNA tethering device, read the paper here: authors.elsevier.com/c/1gK103vVUPK9… Huge thanks to all collaboration partners W.Roos, B.Steigenberger and C. Junge! #cryoEM, #DNArepair, #MRN

Postdoctoral positions available in Nussenzweig lab to study mechanisms involved in DNA repair- 1st position (wet lab) focuses on using cutting-edge cellular, molecular, and genomic tools. 2nd uses computational approaches to study DNA repair.

Check out our latest story in Molecular Cell. Our team pairs the dTAG system with deep genomic analysis to determine the spatiotemporal role of SMARCA5 in the maintenance of chromatin structure and function. bit.ly/3GNCalx

Researchers from the Osheroff Lab were instrumental in the development of the first new antibiotic treatment for uncomplicated urinary tract infections in more than 20 years. Their collaborators GSK will soon be filing for FDA approval. news.vanderbilt.edu/2023/01/18/van…

🧬🛠️ We had an amazing time at the Mammalian DNA Repair GRC in Ventura, CA. Fantastic presentations and discussions at a great location. 🙏 to Patricia Opresko, PhD and Roger Greenberg for organizing. Can't wait for the next one! Gordon Research Conferences #DNARepair

Please forward this to any senior graduate students you know. Should be lots of fun! I can't wait to meet the participating trainees and hear about their research!

Our latest termination paper is online! 🐸🧬➡️⬅️🧬Key points: - RTEL1-MCM10 is a 'backup' mechanism for when TOP2 is compromised - MCM10 promotes RTEL1 binding/function - RTEL1-MCM10 don't regulate topology but do act as a general stalled fork response cell.com/cell-reports/f…

AP endonuclease 2 (APE2) as an emerging therapeutic target– More from our special collection on DNA repair and cancer therapeutics. From Shan Yan UNC Charlotte Biological Sciences academic.oup.com/narcancer/arti…

We're looking for a new research technician to join our lab! Reasons to join: 1. Great science 🐸🧬 2. Fun & supportive environment 😃🙌 3. Excellent training record 🥇🎉 tinyurl.com/DewarLabRA23 Please share with any class of '23 graduates who might be interested!

The Cimprich lab has research assistant positions available.  If you (or someone you know) might be interested please apply here:    careersearch.stanford.edu/jobs/life-scie… careersearch.stanford.edu/jobs/life-scie…

Happy to share our study about the role of Top2 complexes in different chromatin contexts! We find that Top2 catalytic inhibition leads exclusively to instability of the repetitive genome which depends on Top2a. For more details of how, please read: biorxiv.org/content/10.110…