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A story of The Masters👑- Regulation of the master chromatin organizer🧬 by the master regulator of hypoxia💥!! #CTCF #HIF1a Out now in Cell Reports It was a great experience working on this project☺️Sanjeev Shukla Parik Kakani rushikesh joshi #DeepakPant ERPLab@IISERB IISER Bhopal

Many congratulations to Prof. Sanjit Konar, Prof. Vishal Rai (Chemistry) and Prof. Sanjeev Shukla (Biological Sciences) on being elected as Fellows of the National Academy of Sciences, India (NASI). We wish them many more laurels in the future. #NASI #achievement #iiserb

Congratulations Sanjeev Shukla 🎉👏

Interested in how epigenetic modifications impact alternative splicing in cancer? Join my lab at IISER Bhopal! We're exploring this exciting area with cutting-edge techniques. #cancerepigenetics #alternativesplicing #IISERBhopal ERPLab@IISERB

Old enemies, new perspectives? Explore the interplay of epigenetics and alternative splicing in cancer in this new review by @madhurapandkar from @erplab_iiserb, who is now a postdoc at Northwestern University; doi.org/10.1042/BCJ202… #Biochemj #iiserb

Preprint alert: Kudos to Deepak Pant from @erplab_iiserb for uncovering how YEATS2 & GCDH interplay drives histone crotonylation & EMT in #HNSCC. New mechanistic insights! #epigenetics #metabolism doi.org/10.1101/2024.0… IISER Bhopal

New preprint! Cheers to SRINIVAS ABHISHEK MUTNURU from @erplab_iiserb for revealing PRMT5-mediated histone methylation promotes EMT and invasion in breast cancer hypoxia by altering TCF3 splicing. #cancerbiology #hypoxia @iiserb doi.org/10.1101/2024.1…

Excited to share our new study in Cell Reports showing that CTCF-mediated loop switches alternative splicing and promotes EMT. Parik Kakani, ERPLab@IISERB, Dimple Notani. Thanks to Department of Biotechnology IISER Bhopal cell.com/cell-reports/f…

Congratulations to Parik Kakani for two consecutive amazing publications in Cell Reports. Working on these studies was a great experience for me, thank you!!! Sanjeev Shukla ERPLab@IISERB IISER Bhopal

A recent article from Dr. Shukla’s lab on “Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer” is published in the Cell Reports. doi.org/10.1016/j.celr…. Department of Biotechnology, IISER Bhopal

Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer dlvr.it/THqfx3

A recent study provides critical insights into the mechanisms by which tumor #hypoxia, through #CTCF and #alternativesplicing regulation, promotes #EMT in breast cancer cells. The identification of the HIF1a-CTCF-COL5A1 axis and the potential for its therapeutic targeting

I am excited to share our new paper on the role of #ATF3 in promoting #EMT in hypoxic breast cancer via regulating the #alternativesplicing of #P4HA1. Congratulations to the all fantastic authors and to Shruti Dhamdhere who led this study!!! 🥳🥳

Excited to share our study which explores the role of #Hypoxia induced #ATF3 in #BreastCancer invasion via enhancement of an invasion conducive ECM and regulation of #P4HA1 splicing. Thanks to Sanjeev Shukla Anamika Bansal Parik Kakani ERPLab@IISERB IISER Bhopal

#authorinterview Shruti Ganesh Dhamdhere Shruti Dhamdhere ERPLab@IISERB IISER Bhopal talks about her work on "Adaptive stress response genes define invasiveness of hypoxic breast cancer" biopatrika.com/academia/resea… via Biopatrika

Exciting PhD opportunity! Join our lab ERPLab@IISERB (sshuklagroup.iiserb.ac.in) to explore the fascinating interplay of epigenetics & alternative splicing in cancer. Dive into cutting-edge research! Apply now: phdadmission.iiserb.ac.in #PhD #Cancer #Epigenetics #AlternativeSplicing

In this review, Anchala Pandey, Ankit & Jithin from @erplab_iiserb unravel the complex relationship between autophagy, aging & cancer. The review highlights autophagy's potential as a therapeutic target to combat age-related diseases and cancer progression. sciencedirect.com/science/articl…

#CDFDSeminars Excited to host Prof. Sanjeev Shukla at BRIC-CDFD! Join us as he explores cutting-edge research on gene regulation and chromatin dynamics. 🗓️ May 1, 2025 | 🕛 12:00 PM 📍 CDFD Seminar Hall

Exciting work from Anchala Pandey and Jithin ERPLab@IISERB. Our latest study uncovers the SRSF9-BNIP3 axis, demonstrating how alternative splicing orchestrates both autophagy & metabolic reprogramming under hypoxia. IISER Bhopal jbc.org/article/S0021-…