
Stephen Stone, MD
@diabetesninja
| #PedsEndo & #PhysicianScientist | Amateur Medical Illustrator | Dabbles in #Python | Tweets are my own | RT != Endorsement | bmc.link/DiabetesNinja |
ID: 701620917453991937
https://stonelab.wustl.edu 22-02-2016 04:13:57
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Angela Rao at #ENDO2025 explored how GLP-1 therapies may complement bariatric surgery: 💊 Adjunctive GLP-1 use is promising—but data are not yet statistically significant 🧩 It’s a complex issue requiring individualized care ✅ Pre- and post-op GLP-1 Endocrine Society Angela Rao, MD


At #ENDO2025, Rossella Cannarella shared exciting data on tirzepatide for men with metabolic hypogonadism: 🧬 Benefits go beyond weight loss 🍆 Improves sexual function 👶 Fertility implications on the horizon? Endocrine Society Rossella Cannarella


Important reminder from Melanie Haines at #ENDO2025: 🏋️♀️ Preventing muscle loss is a key consideration in GLP-1 therapy 👩🦳 Women + older adults are at highest risk 🦴 Potential links to increased bone resorption via CTX Endocrine Society Melanie Schorr Haines



Iza Machado at #ENDO2025: 🧬 Puberty timing matters—for life! 📊 Data from Brazil show: •Early menarche → ↑ cardiovascular risk •Late menarche → ↑ coronary artery disease Puberty isn’t just a phase—it’s a predictor. Endocrine Society


Meet the professors at #ENDO2025! Onno Holleboom & Eveline Bruinstroop shared key tips for managing MASLD: 📈 FibroScan & FIT-4 = essential, non-invasive tools 🧬 GLP-1s & THRβ agonists also showing promise Endocrine Society


Dinner with some of the greatest Peds Endos I’ve ever met! Grateful for the mentorship, collaboration, and laughter that make #ENDO2025 unforgettable. Endocrine Society #PedsEndo #ENDO2025


Come visit my poster at #ENDO2025! 📍 MON-573 | 12:00–1:30 PM 🧬 Exploring novel SLC2A4 (GLUT4) variants in atypical young-onset diabetes Part of the #RADIANT study and proud to share this work with the rare diabetes community! Endocrine Society


Jens Holst at #ENDO2025 made a powerful case: 💡 GIP is the most important incretin hormone 🧠 Incretins act centrally—like a “brake” 🫀 Reduce CV risk, inflammation, diabetes, sleep apnea, MASH 💬 Now is the time to support lasting lifestyle change. Endocrine Society


Grant-writing wisdom from Tracy Rankin at #ENDO2025: 📌 Know when to contact your PO vs SRO 🧠 Plan for pitfalls—technical and conceptual 🗓️ Timelines! 💬 Know your audience: peers, reviewers, and people outside your niche 💡 And above all—be resilient! Endocrine Society


Luca Persani for Federica Marelli shared innovative approaches to thyroid hormone resistance at #ENDO2025: 🧬 Zebrafish = a powerful model for VUS in THR 📉 THRβ easier to dx via TFT signature 🧪 Chimeric TRα1 mutants? Isoform-specific insights coming Endocrine Society


🚨 Genetic breakthroughs in 46,XY DSD at #ENDO2025! Vincent Harley shared: 🧬 3 cases of MAP3K7 variants affecting Sertoli cells 🧠 DMRT3 variants may alter estrogen signaling & transcription Fascinating mechanistic insights into testis development. Endocrine Society


Robert Semple at #ENDO2025 unveiled an ambitious approach: 🧬 Deep mutational scanning of every possible variant in the insulin receptor! •Cysteine-rich domains = critical •Discriminates mAb-responsive variants •Useful for variant interpretation Endocrine Society


What’s next in obesity therapy? Christoffer Clemmensen’s #ENDO2025 session ideas: 💉 GLP-1 changed the game 🧬 Now: dual, triple, & quad receptor agonists (GLP-1, GIP, Amylin, Glucagon) 🧠 Neuroplasticity → potentiates GLP-1 🧪 Ghrelin—may prevent regain Endocrine Society


That’s a wrap on an amazing #ENDO2025! So grateful for the science, the connections, and the opportunity to sketch my way through it all. 🎨 What was your favorite sketch? 🧠 What idea are you still thinking about? Thanks Endocrine Society for an inspiring week!


The ACMG has just published a statement on metabolomics for inborn errors of metabolism, co-authored by Dr. Duque Lasio. WashU Medicine Pediatrics CATDOG_GENES 👏kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…


