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Great work from @JosephineBotsch and bastian bräuning from the Schulman department to uncover new structural properties of Doa10 (yeast)/MARCH6, the Ring-E3 ligase that initiates destruction of SQLE, rate-limiter of cholesterol synthesis. Love the lipids! rdcu.be/dvzsJ

German-Israeli Project Cooperation (DIP) DFG public | @[email protected] funds new research collaboration between Technion Israel, Ivan Đikić Goethe-Universität and Helmholtz Munich | @HelmholtzMunich Universität München to understand and target degradation resistance in #cancer aktuelles.uni-frankfurt.de/english/joint-…

An international research project receives funding to investigate the extent to which #oncoproteins are subject to enhanced stabilization, a typical characteristic of many aggressive and therapy-resistant #cancer types. @diefenbacherlab.bsky.social lmu.de/en/newsroom/ne…

Fresh from the truck, our newest #addition to the team Helmholtz Munich | @HelmholtzMunich Institute of Lung Health and Immunity The DZL Academy @diefenbacherlab.bsky.social ! The benchtop #confocal #microscope from Oxford Instruments

For those who want to learn about the latest on #COPD, do not forget to sign up for this exciting postgraduate course at ATS 2024! Also an opportunity to meet many of COPD_iNET researchers in person! Please RT

Institute of Lung Health and Immunity Helmholtz Munich | @HelmholtzMunich new paper alert! Want to know more about fibroblast transitional states in lung fibrosis? Check this out ERS from our own Herbert B Schiller and Gerald Burgstaller (equal contribution) and many more people from our Institute and other places.

🎙️#Interview with PI Prof. Markus Diefenbacher: Get to Know our Expert for Lung Cancer Institute of Lung Health and Immunity. With his team @diefenbacherlab.bsky.social, he aims to decipher the genetic complexity of #tumors& to develop innovative #therapies against #lungcancer. 👉t1p.de/5rjhb #Lung

That‘s how our Institute of Lung Health and Immunity PIs meet. Happy to have the chance to work with some of the smartest, most creative people to create solutions for the future. We did some mean product design today!@AlionderCPC Mareike Lehmann Theodore S. Kapellos Gerald Burgstaller @diefenbacherlab.bsky.social Malte Luecken

Die #DFG richtet zur weiteren Stärkung der #Spitzenforschung an den Hochschulen 11 neue #Sonderforschungsbereiche (SFB) ein, darunter 5 SFB/Transregio (TRR) von mehreren antragstellenden Hochschulen gemeinsam. Forschungsthemen und weitere Einzelheiten: ➡️dfg.de/de/service/pre…

Research network #UbiQancer "Functionalising #Ubiquitin system against #cancer" is now supported by DFG public | @[email protected]. 🫶 Congrats to all members of TRR387 specially to Florian Bassermann TU München . 4 years of science and fun together 😀🙌🥰 More info on: linkedin.com/feed/update/ur…

REGISTRATION OPEN - CANCER RESEARCH SYMPOSIUM 2024 The Crick Come and hear all about the recent advancements in the intrinsic and extrinsic nature of cancer. Plenty of opportunities to network. eventbrite.co.uk/e/crick-cancer… #Cancerconference #CancerResearch

Excited to share our upcoming 2nd Munich-Chicago Lung Conference!!! Registration is open and free but limited to the first 45 participants. Come join Helmholtz Munich | @HelmholtzMunich Northwestern Medicine Institute of Lung Health and Immunity in Munich.

Save the date 👇👇 It will be fun and great science! Join us (registration free) 2 great keynote speakers: Annette and Soni Pullamsetti Lab Helmholtz Munich | @HelmholtzMunich Northwestern Medicine @LMU_Uniklinikum COPD_iNET American Thoracic Society (ATS) ERS Malte Luecken Gerald Burgstaller Roxana Wasnick

#GUTAbstract by @_MarkusVogt Wolf Lab for Tumor Biochemistry et al on "Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2" via bit.ly/3SNQbX0 Paper: bit.ly/3M5SqkW @diefenbacherlab.bsky.social Nevenka Dudvarski Stankovic #Pancreas #PancreaticCancer

#GUTImage by @_MarkusVogt Wolf Lab for Tumor Biochemistry et al on "Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2" via bit.ly/3M5SqkW @diefenbacherlab.bsky.social Nevenka Dudvarski Stankovic #Pancreas #PancreaticCancer

#HelmholtzMunich Contributes Expertise to #DFG Project: Transregio #UbiQancer 💡The 18-million-euro initiative will explore the role of the #ubiquitin system in #CancerTherapies. 👉t1p.de/ap1mk 🧑‍🔬#HelmholtzMunich researchers including Prof. Markus Diefenbacher, Dr.

USP10 emerges as a unique therapeutic target in APC-truncated #ColorectalCancer 🔬nature.com/articles/s4138… @diefenbacherlab.bsky.social #OpenAccess

🚨 Check our latest paper in Oncogen! By combining #proteomics, #spatialtranscriptomics #AlphaFold #organoids and innovative in vivo CRISPR-induced intestinal tumor models, we identified USP10 as a new vulnerability colorectal tumors. Check it out here: rdcu.be/dYz2U

This work was only possible by combining the expertise from labs Universität München Institute of Lung Health and Immunity Helmholtz Munich | @HelmholtzMunich Goethe-Universität Technion Israel Oncode Institute Universität Würzburg #UniWürzburg @RVZ_Wuerzburg UKW funded by DFG public | @[email protected] Deutsche Krebshilfe GRK2243 rdcu.be/dYz2U

This will be my last post here. @Twitter/X: it was nice while it lasted...see you here: @diefenbacherlab.bsky.social