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📢 Job Posting Are you looking for a new challenge in an outstanding scientific environment? We are #hiring a #Scientific #Manager! 👨‍🔬👩‍🔬 If you are passionate about science and enjoy working in an international collaborative environment, please apply now! 😊 MPI for Multidisciplinary Sciences

We are hiring a lab manager. Deadline for application is the 13th of October. Apply here: candidate.hr-manager.net/ApplicationIni…

Nope 🤦‍♀️

Come join us as a postdoc in the JaJa lab at the Netherlands Cancer Institute if you are interested in the molecular mechanisms underlying telomere maintenance by ALT and in findings ways how to target ALT in pediatric cancer treatment.nki.nl/careers-study/…

nature.com/collections/ea…

Our November issue marks the launch of our new Series on best practices in microbiology. We hope it acts as a 'living textbook' with an expanding collection of articles that push us towards better microbiology research. nature.com/collections/fg…

A bit late to state so, but very happy to see this manuscript, nature.com/articles/s4159…, out on DNA Polymerase ε with us here NatureStructMolBiol. A related manuscript nature.com/articles/s4146… out in NatComms, and a piece showcasing the progress accompanying both nature.com/articles/s4159…

What an absolute pleasure to have worked with the brilliant Sonja Lorenz on this article, just out in NatureStructMolBiol. We showcase interdisciplinary experimental approaches to investigate ubiquitination in the developing neuron -> 🧵 rdcu.be/d2miT

Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors rdcu.be/edRwF. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.

A bit late to promote this excellent work reporting the development of BRISC molecular glues (BLUEs) nature.com/articles/s4159…. This paper is the first in a series of insightful ubiquitylation-related manuscripts with disease-related relevance NatureStructMolBiol will publish

On the way to #cshlubiq; the speakers and posters sound top-notch. If you have any questions about NatureStructMolBiol or just want to chat science, please feel free to say hi.

Out NatureStructMolBiol a Review on origin licensing with the most comprehensive (and coolest!) movies on how pre-RC assembly works. Decades of structural and biochemical work are beautifully illustrated. Kudos to Janet Iwasa, John Diffley and Bruce Stillman. nature.com/articles/s4159…

Scientists travel to work. Some continue to travel during their career, some set roots to an adopted country, some return. NatureStructMolBiol will publish 5 pieces on those that returned. The first discusses Dr. Gomes Dias' return to Brazil. Touching+inspiring. nature.com/articles/s4159…

A transcription balance required for genome stability 🧬⚖️ Our work on RNA Pol II transcription speed control by the DNA helicase RECQL5 and the transcription-coupled DNA repair complex is now on ⁦⁦NatureStructMolBiol⁩ #CryoEM #transcription nature.com/articles/s4159…

Insightful work with potential against henipaviruses out NatureStructMolBiol; have a nice read if interested, nature.com/articles/s4159…

New online! Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis bit.ly/4nYQqwI

Proud to share what we hope will be a reference study on human oocyte proteostasis. Young-donor eggs show globally reduced organelle activity vs. somatic cells, with an even steeper drop as they mature. 👇 for Gabriele Zaffagnini 's detailed explanation embopress.org/doi/full/10.10…

On vacation, but so happy this is out and very proud to have had this discussion. I hope that the NatureStructMolBiol readers appreciate it.