C-19 cases up in IND but disease severity isn't. What's dominant variant behind surge? We don't know. INSACOG's last WEEKLY bulletin came out on Jul 11. A/c to Outbreak.info BA.5 is dominant but an INSACOG scientist said BA.2.75 might be the one science.thewire.in/health/explain…

981 new journal articles, preprints, clinical trials, & protocols were added to Outbreak.info's searchable Research Library in the past 7 days: outbreak.info/resources/sear… #SARSCoV2 #COVID19 #openscience

But if you look at the mutation differences of the spike protein between the original Omicron (BA.1) and the BE.* and BF.* that are in Ontario now there are a lot of differences. They look more like a BA.4 or BA.5 than a BA.1 ( outbreak.info/compare-lineag… ). 6/

R346K and R346S, for example, have been around (in substantial numbers) longer than R346T. R346T has just outcompeted them, as one would expect from the Bloom Lab data. (Graph courtesy of Outbreak.info) 12/

On the question of whether XBB.1.5 has more acute severity, we can look at New Jersey for some hints where XBB.1.5 is estimated to have reached dominance around the beginning of this month and where the data shows a general upward trend in hospitalizations, ICUs, and ventilators.

UK Omicron variant soup ... (GISAID genome submissions through outbreak.info)

What’s CH.1.1? Meet #Orthrus, a new wildcard #Omicron strain with a concerning Delta mutation: tinyurl.com/3n9r2mbe H/t Mike Honey Michael Osterholm CIDRAP #COVIDTwitter #sciencetwitter #medtwitter #pandemic #publichealth

It remains critically important to continue tracking endemic #COVID19 in real time. Scientists at Scripps Research demonstrate the use of Outbreak.info as a standardized, searchable source of information on the virus & its variants scripps.edu/news-and-event… @flaneuseks

Scientists present #outbreak.info, a platform that currently tracks over 40 million combinations of #COVID19 Pango lineages and individual #mutations, across over 7,000 locations, to provide insights for researchers, public health officials and…lnkd.in/gRVAAQ4C

Outbreak.info Research Library collects and integrates COVID-19 information from various repositories, enabling 1-stop search for publications, clinical trials, datasets and other sources. nature.com/articles/s4159… G. Tsueng @flaneuseks Kristian G. Andersen Andrew Su Chunlei Wu

Outbreak.info Genomic Reports provides comprehensive and detailed information about SARS-CoV-2 lineages and mutations worldwide which facilitates near real-time genomic surveillance. nature.com/articles/s4159… @gkay92 @flaneuseks Kristian G. Andersen Andrew Su Chunlei Wu

Outbreak.info is a great tool for exploring SARS-CoV-2 lineages worldwide. My favorite tool is the lineage comparison where you can easily see what lineages contain which mutations. This is really helpful when investigating possible recombinants! outbreak.info/compare-lineag…

Que bien ver el artículo de outbreak.info en Nature Methods. nature.com/articles/s4159… durante el año 2020/2021 fue una de mis principales fuentes para generar estadísticas.

Scripps Research scientists @flaneuseks Andrew Su Chunlei Wu have partnered with @NIAIDBioIT to launch the NIAID Data Ecosystem Discovery Portal - a searchable interface of infectious & immune-mediated datasets