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Claude Shannon was the first person to mathematically quantify how efficiently a message can be communicated. Here’s how he did it: quantamagazine.org/how-claude-sha…

Excited to share our work in @NatureImmunol on synovial fibroblasts in rheumatoid arthritis! A wonderful collab between Hospital for Special Surgery (HSS) + Memorial Sloan Kettering Cancer Center with Vianne Gao Laura Donlin, Tom Norman, Christina Leslie and Sasha Rudensky. nature.com/articles/s4159…

Penicillin kills bacteria by making them explode.

Anyone who wants to study #HLA but feels hesitant as HLA is too complicated☹️? Happy to share our paper Nature Protocols describing the up-to-date knowledge on HLA #genetics and step-by-step tutorial for HLA imputation and association with Soumya Raychaudhuri সৌম্য রায়চৌধুরী🥳 nature.com/articles/s4159…

Really excited to share our latest from Kaitlyn A Lagattuta analyzing alpha-beta paired TCR single cell data, linking T cell receptor sequence features to T cell fates. #genomics #Immunotherapy!

When dreams come true.. 😊

Very happy to share a part of my PhD work!

A rewarding team effort to define how T cell activation by checkpoint therapy can result in an INDUCIBLE HUMAN AUTOIMMUNE CONDITION - which resembles rheumatoid arthritis.

Glancing through a review of SLE genetics (tandfonline.com/doi/full/10.10…), I bumped into a familiar plot, which made me revisit the beautiful work by Kamitaki et al. from 2020 on the elegant dissection of the HLA GWAS signal (nature.com/articles/s4158…), which is one of the fine

#AugustIssue | Michael Holers describes the #complement system and its role in #rheumatic and #autoimmune diseases, and discusses complement #therapeutics in these settings, as well as prospects for improving their clinical use. go.nature.com/3rVoNvH

Moving towards a liquid biopsy for Rheumatoid Arthritis synovitis-our updated computer-automated histology pipeline revealed immunoglobulin skewing in synovium is reflected in the blood…. acrjournals.onlinelibrary.wiley.com/doi/10.1002/ar…

"Moving towards a liquid biopsy for Rheumatoid Arthritis synovitis–analysis of computer-automated histology reveals tissue inflammation is associated with immunoglobulin skewing in blood." — Dana Orange, MD, MS #RheumTwitter pubmed.ncbi.nlm.nih.gov/37463182/

🆕 New in nature! Dr. Raychaudhuri (Soumya Raychaudhuri সৌম্য রায়চৌধুরী) and collaborators including Jen Anolik, Laura Donlin, and Deepak Rao constructed a comprehensive RA #synovial tissue reference that revealed diverse cellular composition. Brigham and Women's Hospital 📖 Full story: bit.ly/46a8V70

Excited 🙌 to see our highly collaborative work out today at nature Foundation for the National Institutes of Health NIAMS nature.com/articles/s4158… with A. Helena Jonsson Soumya Raychaudhuri সৌম্য রায়চৌধুরী Jen Anolik Deepak Rao Laura Donlin and Brenner and NIH AMP network!! CU Anschutz Division of Rheumatology CU Department of Biomedical Informatics (DBMI) CU Anschutz Medical Campus

Finally, I thank all of my amazing colleagues for putting this resource together. Too many to list by name, but especially Dr. Fan Zhang ⛵️, A. Helena Jonsson, Aparna Nathan, Nghia Millard along with Kevin Wei, Deepak Rao, Laura Donlin, Jen Anolik, and Michael Brenner.

Nature research paper: Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes go.nature.com/49vlhJO

Glad to see that our #RheumatoidArthritis cell atlas could reveal some pain-related signaling pathways, like HBEGF Laura Donlin 🌟

The #checkpoints enjoying a last night out after #ACR23 ⁦Laura Donlin⁩ ⁦Deepak Rao⁩ ⁦@cappelliMD⁩ ⁦. Science takes a village

"This collaborative study - across HSS, MSKCC and Harvard University - now reports what cell types are activated in autoimmune arthritis caused by cancer immunotherapies." — Laura Donlin, PhD #RheumTwitter pubmed.ncbi.nlm.nih.gov/37506196/

Julian Voss-Andreae is a quantum physicist-turned-sculptor. His work is heavily influenced by his background in science and his blending figurative sculptures can vanish in front of our eyes