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Im long replacement

Everyone wants create BS biomarkers that are “proprietary” but no one wants to actually improve the biomarkers that matter

You can hardly get past the first page of books these days without noticing the signs…

Aim for a low Lp(a) without metabolic dysfunction

If you’re serious about olive oil you source directly from a farm in the middle east or Mediterranean that doesn’t even have a label (im only half joking)

I used Prostate Predict to predict Biden’s probability of survival over the next ten years I made some assumptions such as the cancer being confined to the prostate but is an aggressive form with a PSA of 50

How can anyone watch this video and think this is okay

You can have a “protocol” for weight loss or exercise and claim it works for you - fine But you can’t have a “cancer protocol” based on vibes and bro science 🤦‍♂️

Untreated lp(a) is probably the reason why statins aren’t as effective in increasing overall survival as you would think Most statin studies never included lp(a) which is elevated in ~ 20% of people an oral lp(a) + apoB treatment would be huge

Asked chatgpt to act as a business coach, to help me make a decision After a few questions back and forth it started to upsell me on more services Felt like it was pushing me in the direction with the highest upsell potential Crazy!

Turns out liquid biopsies such as GRAIL might not be useful for early cancer detection as was hoped For Stage I cancer (early, curable): only 16% detection rate in this analysis NHS trial data to come but early indicators seem like it was a failure Disappointing

Is the statement accurate? “Cancer and aging are completely different phenomena. Cancer arises from a single cell with mutations. Aging, on the other hand, is a systemic process: all cells in the body participate.” While I agree that aging is not caused by DNA damage alone,

Very true. I always push people to start doing HIIT instead of zone 2 Way less time commitment and higher impact Yes even if you’re just starting out, you can do gradual HIIT

I tried tirzepatide 2.5 mg for one single dose and it has rewired by brain It’s been 4 weeks since I stopped and I subjectively have twice as much self discipline as before micro-dosing GLPs to break out of a downward cycle of bad eating might be an interesting ‘hack’

Physical activity is nearly as good a predictor of mortality as age

More evidence that aging is mainly caused by up-regulation of growth signaling pathways leading to hyperfunction Inhibition of one pathway alone (mtor for example) leads to upregulation of other pathways which is probably why rapamycin isn’t as effective alone Its like a game