Frederick L. Locke (@drfredlocke) 's Twitter Profile
Frederick L. Locke

@drfredlocke

Oncologist, Immunologist, Cell Therapy and Transplant Expert @MoffittNews • Husband and Father of Five • #Lymphoma #CellTherapy #CARTcells • views are my own

ID: 1453786558360952833

calendar_today28-10-2021 18:12:04

240 Tweet

1,1K Followers

635 Following

Cancer Center @ CHOP (@chopcancercntr) 's Twitter Profile Photo

Our Center recently celebrated its 600th patient treated with CAR T-cell immunotherapy, a groundbreaking “living drug” that utilizes the patient’s immune system to fight cancer. Pioneered at CHOP and Penn Medicine, CAR T has transformed cancer treatment worldwide.

Our Center recently celebrated its 600th patient treated with CAR T-cell immunotherapy, a groundbreaking “living drug” that utilizes the patient’s immune system to fight cancer. Pioneered at CHOP and <a href="/PennMedicine/">Penn Medicine</a>, CAR T has transformed cancer treatment worldwide.
Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

#FollowFriday Meet Hein Liu, MD (Hien D. Liu, MD), a Blood and Marrow Transplant oncologist who specializes in autologous and allogeneic transplants and CAR T-cell therapy. She is the Medical Director of Moffitt’s Apheresis Program and her research focuses on stem cell mobilization

#FollowFriday Meet Hein Liu, MD (<a href="/hiendliu1/">Hien D. Liu, MD</a>), a Blood and Marrow Transplant oncologist who specializes in autologous and allogeneic transplants and CAR T-cell therapy. She is the Medical Director of Moffitt’s Apheresis Program and her research focuses on stem cell mobilization
Dr. Patrick Hwu (@patrickhwumd) 's Twitter Profile Photo

Meet the first patient in the world to receive Tecelra, a groundbreaking engineered cell therapy for synovial #sarcoma. This is a powerful story of resilience and innovation—and I’m so proud of our team Moffitt Cancer Center for leading the way in this area! moffitt.org/endeavor/archi…

Toby Eyre (@tobyeyre82) 's Twitter Profile Photo

Three-year follow-up analysis of first-line axicabtagene ciloleucel in high-risk large B-cell lymphoma (ZUMA-12) ashpublications.org/blood/article/…

Allogene Therapeutics (@allogenetx) 's Twitter Profile Photo

Full Ph1 ALPHA/ALPHA2 cema-cel data in Journal of Clinical Oncology, demonstrating long-term durability of a 1x Tx in r/r #LBCL patients with our investigational allogeneic #CART and 100% CR in patients with low disease burden – the focus of our ALPHA3 trial in 1L. $ALLO Frederick L. Locke Learn more

Sandy Anderson (@ara_anderson) 's Twitter Profile Photo

Are you interested in joining the only mathematical oncology department IMO in a cancer center Moffitt Cancer Center in the world? We have an open rank tenure track position (assistant/associate/full) available now and would love to hear from you! Apply here: …cancer-center-careers.hctsportals.com/jobs/1859278-o…

Are you interested in joining the only mathematical oncology department <a href="/mathonco/">IMO</a> in a cancer center <a href="/MoffittNews/">Moffitt Cancer Center</a> in the world? We have an open rank tenure track position (assistant/associate/full) available now and would love to hear from you! Apply here: …cancer-center-careers.hctsportals.com/jobs/1859278-o…
CIBMTR (@cibmtr) 's Twitter Profile Photo

Dr. Sergio Giralt is now giving the Mortimer M. Bortin Lecture, “Something Funny Happened on My Way to Tandem,” in Ballroom B #Tandem25 ASTCT

Dr. Sergio Giralt is now giving the Mortimer M. Bortin Lecture, “Something Funny Happened on My Way to Tandem,” in Ballroom B #Tandem25 <a href="/ASTCT/">ASTCT</a>
Michael Jain (@michaeldjain) 's Twitter Profile Photo

Interesting, I always wondered why heme biosynthesis comes up as a pathway involved in therapy resistance. Looks like it modulates apoptosis resistance.

Frederick L. Locke (@drfredlocke) 's Twitter Profile Photo

Off-the-shelf CAR-T is here! Our phase 1 trial in Journal of Clinical Oncology shows allogeneic CD19 CAR-T cemacabtagene ansegedleucel (cema-cel) delivers durable remissions in R/R DLBCL: 🔹42% CR rate with median CR duration 23.1 months 🔹No GVHD, ICANS, or severe CRS ascopubs.org/doi/10.1200/JC…

Off-the-shelf CAR-T is here! Our phase 1 trial in <a href="/JCO_ASCO/">Journal of Clinical Oncology</a> shows allogeneic CD19 CAR-T cemacabtagene ansegedleucel (cema-cel) delivers durable remissions in R/R DLBCL:
🔹42% CR rate with median CR duration 23.1 months
🔹No GVHD, ICANS, or severe CRS
ascopubs.org/doi/10.1200/JC…
Dr. Patrick Hwu (@patrickhwumd) 's Twitter Profile Photo

Years ago, we decided cell therapies were going to be critical to cancer care and research, and today Moffitt Cancer Center is a leader in the field. It didn’t happen by chance. #ThursdayThoughts ➡️ How are you creating your future?

Years ago, we decided cell therapies were going to be critical to cancer care and research, and today <a href="/MoffittNews/">Moffitt Cancer Center</a> is a leader in the field. It didn’t happen by chance. #ThursdayThoughts 

➡️ How are you creating your future?
OncoDaily IO (@oncodailyio) 's Twitter Profile Photo

Advancing CAR T-Cell Therapy - Off-the-Shelf Allogeneic Approach - Yan Leyfman, MD Frederick L. Locke oncodaily.com/science/yan-le… #Cancer #ImmuneOnc #IO #ImmunoOncology #Immunotherapy #MedEd #MedX #MedNews #Health #Medicine #OncoDaily #Oncology

Ciara Freeman (@freemanlciaramd) 's Twitter Profile Photo

Thanks to all my amazing Moffitt Cancer Center collaborators - but special thanks go out to Dietrich Werner Idiaquez for your BEAUTIFUL images of sBCMA expressing myeloma cells that grace the cover of Blood this week

Thanks to all my amazing <a href="/MoffittNews/">Moffitt Cancer Center</a> collaborators - but special thanks go out to Dietrich Werner Idiaquez for your BEAUTIFUL images of sBCMA expressing myeloma cells that grace the cover of Blood this week
Bruce Levine, Ph.D. 🇺🇦🥼🔬🧬🧪💉 (@bllphd) 's Twitter Profile Photo

Big News for CAR T cell delivery to patients and monitoring: FDA Eliminates Risk Evaluation and Mitigation Strategies (REMS) for Autologous Chimeric Antigen Receptor (CAR) T cell Immunotherapies #FDA #Tcellrx #immunotherapy fda.gov/vaccines-blood…

Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

Join us in congratulating Moffitt Cancer Center President and CEO, Patrick Hwu, MD, for being recognized by his peers and the Tampa Bay Business Journal as one of Tampa Bay’s 2025 Most Admired CEOs. This recognition reflects his leadership in advancing Moffitt as Florida’s

Join us in congratulating Moffitt Cancer Center President and CEO, Patrick Hwu, MD, for being recognized by his peers and the Tampa Bay Business Journal as one of Tampa Bay’s 2025 Most Admired CEOs.

This recognition reflects his leadership in advancing Moffitt as Florida’s