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Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases. A new Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: hubs.li/Q03dRtHg0

Want to master bioinformatics data visualization? Learn ggplot2! 🧵👇

Thread of natural sources of different medications. We can thank the Gila Monster for modern GLP-1 drugs like Ozempic

Timescales in Cell Biology

1042 people with at risk Steatotic Liver Disease- 38% are reclassified when reassessed in 2 years! Over 60% with MetALD/ALD and 38% with MASLD change subclass SLD is a dynamic spectrum 👉 people should be reassessed- ALCOHOL AND CMRF! cghjournal.org/article/S1542-…

I shared my thoughts in a Nature Medicine comment on the urgent need for more standardized benchmarks in #AI for biomedicine. nature.com/articles/s4159…

In 1945, six women pulled off a computing miracle. They programmed the world’s first computer—with no manuals, no training. Then, a SINGLE assumption erased them from tech history for decades. The story of how ONE photo nearly deleted computing’s female founders: 🧵

We're entering a new era of #Alzheimers blood testing—fully automated platforms now deliver fast, accurate #pTau217 results for use in primary & secondary care. Proud to share senior authorship and proud of this multi-centre European collaboration. 🔗 nature.com/articles/s4159…

Making a heatmap is an essential skill for a bioinformatician. But you probably do not understand heatmap. 7 reading resources to understand heatmap! 🧵

Stem cell therapy for Parkinson’s disease has entered a new era. Two nature studies demonstrate that pluripotent stem cell–derived dopamine neurons can survive, restore function, and potentially change the treatment paradigm for this neurodegenerative disease.

🌎Important global perspectives are being shared this morning at #EASLCongress during the Global Liver Forum on tailored approaches to hepatic encephalopathy. Experts from Europe, Latin America, Asia and beyond are reflecting on the latest guidelines, real-world management

Excited to hear the wonderful ⁦Annalisa Berzigotti⁩ give the JP Benhammou lecture ⁦EASLnews⁩ #EASLCongress ⁦Debbie Shawcross⁩ ⁦Aleksander Krag⁩ ⁦Rui Castro⁩

Just published! Even NASA cleanrooms—designed to be ultra-clean—harbor resilient, novel bacteria. 26 new species were found, some forming biofilms, resisting radiation, and producing biotech-relevant compounds. Check it here: microbiomejournal.biomedcentral.com/articles/10.11…

🚨 New in Nature Communications: We present a spatial multi-omics platform that maps the metabolome, lipidome, and glycome from a single brain section. Combining MALDI imaging with our computational tool Sami, we reveal metabolic diversity in health and Alzheimer's disease. 🔗

Delighted to share this new study led by Lachlan Gilchrist now published in BMC Medicine Here we performed comprehensive analyses exploring how plasma metabolites may causally influence psychiatric and neurodegenerative diseases. Some of our key findings below 🧵

Carlos Alcaraz has won his 5th Grand Slam title at the EXACT same age as Rafa Nadal when he achieved the same feat. Some things are just meant to be 🇪🇸🤩

Carlos Alcaraz, historical. #RolandGarros

Apple acaba de publicar un paper con un título demoledor: *The Illusion of Thinking*. Y no es metáfora. Lo que demuestra es que los modelos de IA que usamos todos los días —sí, tipo ChatGPT— no piensan. Ni un poco. Solo imitan que lo hacen. Te explico: 🧵👇

Happy to share this RCT from GALAXY in people with ALD Out today in Nature Portfolio rdcu.be/eujFT The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial

En 1987, Freddie Mercury conocía en el hotel Ritz de Barcelona a uno de sus ídolos, Monserrat Caballé. Aquella noche sería el inicio de una amistad que traería al mundo el mejor himno de unos Juegos Olímpicos jamás creado: Barcelona. Tira del hilo 🧵👇🏽👇🏽👇🏽