LiMCA is a tool for co-profiling 3D genome structure and gene expression at the single-cell level, applied here to study olfactory receptor gene selection. nature.com/articles/s4159…

Super excited about the 2024 Single-Cell Genomics Gordon Research Conference to be kicked off on Sunday, May 19!!! grc.org/single-cell-ge… We are grateful to Stephen Quake, Joakim Lundeberg, Aviv Regev, and Jonathan Weissman's Lab for accepting our invite as the keynote speakers. It was

Excited to attend the GRC single-cell and spatial omics meeting next week in Les Diablerets! Looking forward to learning about ongoing projects and hearing paper pitches.

Research Highlight by Lei Tang: Xiao Wang describes a synthetic approach to make multitailed mRNAs for prolonged translation. Original paper: nature.com/articles/s4158… Highlight: nature.com/articles/s4159…

Beautiful weather landing Geneva and amazingly the sunset time is after 9pm!

More about the t-SNE, UMAP story....So. There's a figure in a nature paper undergoing revision. Yah, no, not *that* paper. This one is by AllofUsResearch and the figure caused a bit of a stir because of how it documents diversity of a study population. nature.com/articles/s4159…

Research Highlight by Lei Tang: A nascent RNA sequencing method (scGRO-seq) enables studying ongoing transcription at genes and enhancers with single-nucleotide resolution. Original paper: nature.com/articles/s4158… Highlight: nature.com/articles/s4159…

We're so excited to present this special issue! It was a true team effort, with contributions from all the Nature Methods editors: Lin Tang, Dr. Arunima Singh, Rita Strack, Madhura Mukhopadhyay, Lei Tang, Nina Vogt and Vivien Marx🐘📬⛅️.

Research Highlight by Lei Tang: a CHARMing epigenetic silencer. Original paper: science.org/doi/10.1126/sc… Highlight: nature.com/articles/s4159…

Research Highlight by Lei Tang: The Stafforst group found that G•U wobble base pairs can mitigate bystander editing and thus improve precision in RNA editing. Original paper: nature.com/articles/s4158… Highlight: nature.com/articles/s4159…

Please join us for our free Technology Live Virtual Symposium on Spatial Biology this October 29th! natureconferences.streamgo.live/spatial-biolog… Speakers include Rong Fan, Andrea Radtke, Long Cai, Sarah Teichmann and many more!

Mountain view at Huangshan

Our 20th anniversary issue also includes anecdotes from past editors Daniel Evanko, Nicole Rusk, Natalie de Souza, Erika Pastrana, Tal Nawy, and current editors Allison Doerr, Nina Vogt, Rita Strack, Lei Tang, Dr. Arunima Singh, Lin Tang and Madhura Mukhopadhyay. nature.com/nmeth/volumes/…

Research Highlight by Lei Tang: the Brangwynne group utilizes synthetic condensates to explore the viscoelastic properties of chromatin. RH: nature.com/articles/s4159… Original paper: cell.com/cell/fulltext/…

What a delightful cake!

Registration is still open for this free virtual symposium on SPATIAL BIOLOGY next Tuesday the 29th! Please join us for a packed day of great science! Organized by Lei Tang and Rita Strack along with editors Nature Genetics Nature Biotechnology nature

Spatial Proteomics named 2024 Method of the Year!

Feb RH on in vivo CRISPR screening!

Tomorrow is #LoveYourPetDay, a very important day for us at Springer Nature. We love to celebrate the wonderful pets that bring joy to our lives and inspire our work. With our #PetsOfSN from around the world, we hope to showcase the amazing bond we share with our pets.

We are recruiting！