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🔎 ACG Case Reports Journal 🔍 Novel Use of the Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition for the Treatment of Crohn's Disease During Pregnancy Ukovic, et al. 👉 bit.ly/3KAfl7w Bianca Ukovic Brooke Chapman Dr Julien Schulberg Matthew Choy #GItwitter #GIfellows

Outcomes out to 12 months after sequential use of high‐dose tofacitinib following infliximab in acute severe ulcerative colitis - Eqbal - 2023 - Internal Medicine Journal - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/im… patrick Matthew Choy

An Australian designed medical invention is giving new hope to sufferers of Crohn's disease. A Melbourne dad has undergone world-first surgery for an implant using electrical stimulation to prevent gut damage. youtu.be/tg5qz7JP6Fg Emma O'Sullivan #7NEWS

Dr Matthew Chou presenting the PREDICT UC trial of IFX in ASUC—primary endpoint negative; those with intensified groups achieved good outcomes earlier, but no differences after 3 months #DDW2024

#Choy: PREDICT UC: OPTIMISING INFLIXIMAB INDUCTION THERAPY FOR ACUTE SEVERE ULCERATIVE COLITIS - A RANDOMISED CONTROLLED TRIAL #DDW2024 Y-ECCO Fernando Gomollón Florian Rieder Ashkan Rezazadeh MD Aline Charabaty, MD, FACG, AGAF Irina Blumenstein Natalia Queiroz Sophie Restellini

Choy - Intensified (10 mg/kg) and accelerated (5 mg @ shorter intervals) not superior to standard IFX dose for induction of response in ASUC #colitis patients w moderate-severe endoscopic activity. More is not better X when Albumin is low #DDW2024 #IBD Very important study

PREDICT UC trial optimizing infliximab dose in patients with #ASUC Initially no differences at day 8 BUT ✅intensified better if albumin<25 ✅ intensified better if crp>50 Presented by Matthew Chuen Seng Choy at Digestive Disease Week #DDW2024

Congratulations to Matthew Choy and his team for presenting their PREDICT UC findings re the utility of intensified IFX dosing in #ASUC at DDW! Austin Health Australia New Zealand IBD Consortium (ANZIBDC)

Long-term continuous terlipressin infusion improves cardiac reserve in patients with decompensated cirrhosis - Clinical Gastroenterology and Hepatology cghjournal.org/article/S1542-…

New research - Choy et al Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial thelancet.com/journals/langa… #IBD #GITwitter Matthew Choy Christopher Li Wai Suen

PREDICT-UC - Intensified vs standard dose IFX induction for steroid-refractory ASUC Two randomisations: (1) 1st IFX dose of 10 mg/kg vs 5 mg/kg (2) Patients in 5 mg/kg group were re-randomised to a standard or accelerated induction strategy #GITwitter #IBD (1/2)

Intensified infliximab rescue strategies for acute severe ulcerative colitis - results from the PREDICT-UC trial in The Lancet Gastroenterology & Hepatology A summary 👉 linkedin.com/posts/rob-brie… #GITwitter #IBD

Should Intensified Infliximab for Refractory Acute Severe UC Be Nixed? medpagetoday.com/gastroenterolo… via MedPage Today

Outcomes in ASUC based in cytokines and fecal biomarker from the PREDICT-UC trial Higher IL-6 predicted worde steroid and antiTNF response Fecal TNF at day 3 predicted IFX no response #ECCO2025

Well done to the amazing PREDICT-UC team at #ECCO2025. Two amazing clinically relevant DOPs from a team leading the charge in refining ASUC management Matthew Choy Ashish Srinivasan MD PhD

The pickle man himself Elliot Tapper presenting on cramps in cirrhosis Austin Health ACTER Advanced Liver Disease Symposium.

Marie Sinclair presenting her novel use of continuous terlipressin infusions for ascites and HRS Austin Health ACTER Advanced Liver Disease Symposium.

📌Biologic safety in #IBD post liver transplant - what’s safest? 💊Gut-specific (VDZ) v systemic (aTNF, UST) agents = similar infectious events ⚠️ Steroid co-therapy = ⬆️ severe infections Out in AP&T 🔗doi.org/10.1111/apt.70… 👏Congrats #SimoneChin! #GITwitter #livertwitter