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Drug Discovery News

@drugdiscovnews

We provide engaging stories that help life science researchers keep current on the latest news in translational, preclinical, and clinical research.

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linkhttp://drugdiscoverynews.com calendar_today20-02-2020 14:25:14

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Bone marrow transplantation has been a concept since the 19th century, but it wasn’t until World War II that it rose to the foreground of medical research. Explore the history, hurdles, and advancements that have shaped bone marrow transplantation: ow.ly/Uci350UEyek

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Our President and CEO, Sabrina Martucci Johnson , recently spoke with Drug Discovery News about her thoughts on the biggest innovations in drug discovery in 2025, and how the focus on diversity in clinical trials could be a new opportunity. Read more: drugdiscoverynews.com/predicting-202…

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In this webinar, Le Zhang will discuss how she paired single cell transcriptomics and proteomics to reveal distinct brain cell types and cellular interactions that drive neuroinflammation in Parkinson's disease. Register now: ow.ly/5sPN50UBrqb

In this webinar, Le Zhang will discuss how she paired single cell transcriptomics and proteomics to reveal distinct brain cell types and cellular interactions that drive neuroinflammation in Parkinson's disease.

Register now: ow.ly/5sPN50UBrqb
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A new protein-based system delivers drugs across the blood-brain barrier. The non-invasive transport vehicle could treat brain diseases with fewer doses and longer-lasting effects. ow.ly/qaRU50UBqI6

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A recent study using single-cell DNA sequencing found that healthy breast tissue contains a small percentage of aneuploid cells — cells with abnormal chromosome numbers. Read more: ow.ly/tSKK50UGslJ

A recent study using single-cell DNA sequencing found that healthy breast tissue contains a small percentage of aneuploid cells — cells with abnormal chromosome numbers.

Read more: ow.ly/tSKK50UGslJ
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In this webinar brought to you by BD Biosciences, Gisele Baracho will discuss how she combined sequencing and cell sorting techniques to uncover key T cell subsets that drive systematic inflammation in psoriasis. Register now: ow.ly/hSfL50UBri5

In this webinar brought to you by <a href="/BDBiosciences/">BD Biosciences</a>, Gisele Baracho will discuss how she combined sequencing and cell sorting techniques to uncover key T cell subsets that drive systematic inflammation in psoriasis.

Register now: ow.ly/hSfL50UBri5
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New research reveals astrocytes in glioblastomas mirror early developmental stages. Therapies targeting their maturation offer hope for combatting this aggressive brain cancer. ow.ly/3O2J50UC8Vr

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Which drugs working their way through clinical trials are industry leaders watching? đź‘€ Our editors Allison Whitten, PhD and Stephanie DeMarco, PhD talked with biotech and pharma experts to find out! Learn what to keep your eye on in 2025: ow.ly/4Vhy50UGiOB

Which drugs working their way through clinical trials are industry leaders watching? đź‘€

Our editors <a href="/allisonpwhitten/">Allison Whitten, PhD</a> and <a href="/sci_steph/">Stephanie DeMarco, PhD</a> talked with biotech and pharma experts to find out!

Learn what to keep your eye on in 2025: ow.ly/4Vhy50UGiOB
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Researchers developed an oral oxytocin-based painkiller that alleviates chronic abdominal pain in mice by targeting gut-specific receptors. This could offer new treatments for gastrointestinal disorders. Read more: ow.ly/PUO850UIJw5

Researchers developed an oral oxytocin-based painkiller that alleviates chronic abdominal pain in mice by targeting gut-specific receptors.

This could offer new treatments for gastrointestinal disorders.

Read more: ow.ly/PUO850UIJw5
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Editors, Allison Whitten, PhD and Stephanie DeMarco, PhD, asked biotech and pharma leaders about their predictions for 2025. See what these industry experts predict will be the biggest innovations in drug discovery and development this year. ow.ly/SArG50UCxT5

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One mutation is all it takes. New research suggests a single mutated BRCA1 allele can push the cell towards cancer, challenging the two-hit hypothesis. These findings could lead to new strategies for diagnosing and treating breast cancer. Read more: ow.ly/5IHg50UIOC1

One mutation is all it takes.

New research suggests a single mutated BRCA1 allele can push the cell towards cancer, challenging the two-hit hypothesis.

These findings could lead to new strategies for diagnosing and treating breast cancer.

Read more: ow.ly/5IHg50UIOC1
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Innate Pharma's four-pronged NK cell engagers effectively stimulate existing NK cells to target and destroy lymphoma cells, potentially offering a robust alternative to traditional T cell therapies. ow.ly/p3HV50UIJpY

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Mesenchymal stem cells donate mitochondria to T cells via nanotubes, boosting their energy and enhancing their cancer-fighting capabilities. This discovery could improve T cell-based therapies. Read more: ow.ly/Re9x50UIPhc

Mesenchymal stem cells donate mitochondria to T cells via nanotubes, boosting their energy and enhancing their cancer-fighting capabilities. 

This discovery could improve T cell-based therapies.

Read more: ow.ly/Re9x50UIPhc
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In this webinar, Makesh Karpagavinayagam will share how to use advanced analytical software to optimize bioanalytical processes, achieve regulatory compliance, and ultimately deliver safe and effective therapies to patients. Register now: ow.ly/8o2950UBryg

In this webinar, Makesh Karpagavinayagam will share how to use advanced analytical software to optimize bioanalytical processes, achieve regulatory compliance, and ultimately deliver safe and effective therapies to patients. 

Register now: ow.ly/8o2950UBryg
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The proportion of cells with abnormal chromosome numbers in healthy breast tissue increases with age The findings have implications for current and future breast cancer diagnostic approaches. ow.ly/yWh550UGsJ8

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What are the clinical trials to watch in 2025? Biotech and pharma leaders told Drug Discovery News editors which trials they’re most excited about. ow.ly/cWmk50UIJpE

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By chemically modifying oxytocin to resist digestive enzymes, scientists created a stable oral medication that effectively reduces abdominal pain in mice. ow.ly/aoQf50UIJzy

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Our joints need cartilage, but once it’s lost, adults can’t regenerate more. Samuel Stupp’s lab Northwestern developed a new bioactive scaffold that successfully regenerated cartilage in sheep, Allison Whitten, PhD reports. Read more: ow.ly/kCOH50UPTge

Our joints need cartilage, but once it’s lost, adults can’t regenerate more. 

<a href="/SamuelStupp/">Samuel Stupp</a>’s lab <a href="/NorthwesternU/">Northwestern</a> developed a new bioactive scaffold that successfully regenerated cartilage in sheep, <a href="/allisonpwhitten/">Allison Whitten, PhD</a> reports. 

Read more: ow.ly/kCOH50UPTge
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From the invention of western blotting to the development of automated western analysis, protein detection and analysis is reaching new levels of sensitivity, speed, and accuracy. Explore the history in the Science Milestone, here: ow.ly/IzQA50UR9eJ

From the invention of western blotting to the development of automated western analysis, protein detection and analysis is reaching new levels of sensitivity, speed, and accuracy.

Explore the history in the Science Milestone, here: ow.ly/IzQA50UR9eJ