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Krugman: There's no northern-border problem, no fentanyl, and therefore the entire rationale for tariffs is, as everyone knows, a vain delusion beyond the explication of any economic knowledge. And as such they're probably illegal

Beautiful snowy morning. The view from here #ygk on World Cancer Day

Word of the day is 'spuddle' (19th century): to be extremely busy whilst achieving absolutely nothing.

I have never seen a braver, more courageous editorial than this...

Scientific institutions have a long history of anticipatory obedience | Opinion | Chemistry World chemistryworld.com/opinion/scient…

Democracy runs on trust. Dictatorship runs on fear. The moment trust erodes – whether in institutions, elections, or truth itself – democracy crumbles. A quote from a conversation on Real Time with Bill Maher with Bill Maher about the fragile foundations of democracy in the age of AI and

This is written by a Florida judge and posted on face book. Everyone should soare a few minutes and read his words about Canada and the United States

Important correction of misinformation from Bishal Gyawali, MD, PhD, FASCO - this time around the repeated (false) statements Canada is last to authorize new cancer drugs for use and reimbursement.

Come on #ASCO25, this 💯 should have been a plenary! 7% improvement in 8-yr OS w exercise in adjuvant colon ca, greater than benefit for adding oxali to 5-FU (5% at 10 yrs in MOSAIC). Exercise = $ effective, ~0 tox, & gives pts sense of empowerment. Congrats Chris Booth et al!

The potential impact of this RCT is huge. First one to prove that exercise has benefits equal to many standard treatments for cancer. Wow! Congrats to #ChrisBooth, #KerryCourneya eg al. Go Canada! nejm.org/doi/full/10.10…

Wonderful to see this out in the NEJM today. Structured exercise improves survival in colon cancer! Do come to see #ChrisBooth present in hall B1 at 4 30 PM today ASCO nejm.org/doi/full/10.10…

Head of the Security Service of Ukraine Vasyl Maliuk delivered a report regarding today’s operation. An absolutely brilliant result. A result achieved solely by Ukraine. One year, six months, and nine days from the start of planning to effective execution. Our most long-range

Outstanding work by Chris Booth and colleagues - major impact - and showing just what non pharmaceutical interventions can actually achieve!! World Health Organization (WHO) ASCO ESMO - Eur. Oncology

Phase 3 oncology RCTs often report positive results based on alternative end points, but actual improvements in overall survival or quality of life are rare, highlighting need to prioritize these outcomes in future research & regulatory processes. #ASCO25 ja.ma/3FCoVHI

This is a major story from #ASCO25. Randomized phase 3 trial of time of day of immunotherapy infusion. Randomized to infusion before or after 3pm. Early infusion far superior: PFS 11.3 vs 5.7 HR 0.42, OS HR 0.45! Impactful, pragmatic, not costly. This should be a bigger story.

Please beware that there are fake X accounts using my name for alternate therapies - I do not prescribe any such therapies and I also do not offer medical opinions on X.

"There are no Amish with autism" There are "Vaccines aren't tested against placebo" They are "MMR has never been studied as a possible cause of autism" It has. It's not the cause. I apparently need to say this stuff over and over and over and over again. And again.

So lucky to live in #ygk where we are enjoying a fabulous evening of opera highlights with the Kingston Symphony & Cantabile Choirs (including my daughter). Inspiring reminder that humans are capable of much that is enduring and beautiful. An antidote to the darkness of our times

Lupins and Peonies.

Urgent need for updated guidelines on Systemic Anticancer Therapy use at #EndofLife: Our study of 68,000+ patients found use of novel SACT at EOL, including immunotherapy, was associated with indicators of poor-quality #EndofLifeCare. doi.org/10.1200/JCO-24… Journal of Clinical Oncology The Princess Margaret Cancer Foundation