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🧬 G protein-coupled receptor kinase 5 (GRK5) variant linked to #platelet reactivity and thrombin response. New study shows platelet-specific GRK5 mutants increase pulmonary embolism risk. Andrew Johnson Craig Morrell Elsevier Hematology Learn more: rpthjournal.org/article/S2475-…

🩸 LAIR-1 and PECAM-1 inhibit #platelet activation via the same pathway. Christopher Smith @zoltannagyphd @phgeer @yotissenis @alexandramaz1 show double knockout mice have increased platelet count but normal thrombus formation. Elsevier Hematology ISTH Discover more:

🧬 What does “cure” mean for hemophilia? @liekebaas, Rieke van der Graaf, and SYMPHONY consortium explore the ambiguous use of “cure” in hemophilia, relating it to health and disease concepts. Should we define it clearly? Read more about it here: rpthjournal.org/article/S2475-… Elsevier Hematology

🩺 Platelet reactivity linked to pump thrombosis in LVAD patients. David Mutschlechner and team's research shows high residual #platelet reactivity as a potential risk marker. Elsevier Hematology ISTH Check out the data here: rpthjournal.org/article/S2475-…

Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) is rare but serious. This study of 70 children found most had mild to moderate bleeding, with no exact correlation between thrombin levels and bleeding severity. Elsevier Hematology rpthjournal.org/article/S2475-…

Age & Thrombosis: Nox2’s Role? In aged mice, deleting Nox2 didn’t reduce platelet ROS, activation, or thrombosis. Targeting other pathways may be key to tackling age-induced thrombosis. New insights into aging & clotting dynamics! Elsevier Hematology rpthjournal.org/article/S2475-…

Confused about possible biomarkers for blood cell aging? Check out this review by Wolfgang Wagner, including exploration of how transferable such markers are between mice and humans - Experimental Hematology exphem.org/article/S0301-… ISEH Elsevier Hematology

Check out interview with Dr. Elaine Dzierzak by Dr. John Crispino in Elsevier Hematology! Elaine & Bigas/Espinosa Lab edited Special issue “Making Blood” featuring a beautiful cover by Elaine. The interview explores “Developmental Clock” in natural and artistic ways!! bit.ly/4gAay3L

Submit your next paper to Blood Global Hematology (Blood Global Hematology). The new #openaccess journal from ASH, led by Jorge Cortes, MD (Jorge Cortes MD) Find out more: spkl.io/6018fbrbI

Check out our new review published in ISEH journal Experimental Hematology, asking the question: to what degree is HSC dysfunction responsible for hematologic aging exphem.org/article/S0301-… written by Fenia Fotopoulou Charles Dussiau Esther Rodriguez Correa Elsevier Hematology

Blood Global Hematology (Blood Global Hematology) is inviting submissions! The newly launched #openaccess journal from the ASH. Find out more: spkl.io/6017fbrjl

Discover "The Developmental Clock"—a fascinating intersection of art and science! Explore how creativity and scientific inquiry come together to enhance our understanding of development. #ArtAndScience #Innovation #DevelopmentalClock Read here: spkl.io/6017fe4Q1

Submit your next paper to Blood Global Hematology (Blood Global Hematology). The new #openaccess journal from ASH, led by Jorge Cortes, MD (Jorge Cortes MD) Find out more: spkl.io/6013fbrdV

Join us on Feb 26th for #PhenoTips Speaker Series: “The Undiagnosed Hackathon: Driving Diagnosis Through Global Collaboration." Celebrate the upcoming #RareDiseaseDay with insights from global experts including 3 Rare journal board members. Register now! spkl.io/6010flzJ4

In observance of #RareDiseaseDay, access this article "Economics, Externalities, and Rare Disease" in the journal, Rare! Explore how rare diseases impact healthcare economics, the hidden costs, and externalities affecting patients and society. spkl.io/6010fm5OA

In observance of #RareDiseaseDay, check out the latest study protocol in Rare on measuring health-related quality of life in solid rare cancer patients. Learn about innovative methods to assess the unique challenges faced by these patients. spkl.io/6012fm5ww

Osmosis & Elsevier continue the Year of the Zebra initiative for a 3rd year, spotlighting rare disorders. Monthly videos on symptoms, diagnosis & treatment will educate many. Celebrate the 2nd year of Rare, the journal for open research on rare diseases. spkl.io/6011fmApx

On Apr 29, Rare celebrates Global Undiagnosed Day! Seeing a child/adult w/ undiagnosed diseases on Apr 29? Share your story! Join virtual roundtable (Apr 30) to present a case (w/ family consent). Register: spkl.io/6013faAPB. Wilhelm Foundation (UDNI member) supports!

On Apr 29, Rare celebrates Global Undiagnosed Day! Seeing a child/adult w/ undiagnosed diseases on Apr 29? Share your story! Join virtual roundtable (Apr 30) to present a case (w/ family consent). Register: spkl.io/6019faARF. Wilhelm Foundation (UDNI member) supports!