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Work-life balance getting a workout today when Girls of Steel Robotics robotics Lego camp demo day overlapped w/ grant review! 😅 Photo credit Matt MacDonald 🙏🏼

🚨 PFC twitter 🚨 I am guest editing a special issue of Neuropharmacology on PFC function in neuropsychiatric diseases this year. First deadline will be 10/31. Please reach out if you are interested in submitting a review or research article

Awesome hosting you!

Had a great time presenting some of the latest work from Phillips Mood & Brain Lab at ISBD and learning from others in the field doing exciting work on #BipolarDisorder #ISBD2023

Let's reinvent how we assess neuropsychiatric disorder symptoms. Not all can be quantified/Likert-style rated. To better capture complex symptoms/sensations (e.g. brain feels like it's on fire), we need more creative measurement/reporting methods. We miss what we don't ask about.

Applications for the Neuropsychopharmacology Editorial Internship are now being accepted! This was a very rewarding professional development experience where I got to contribute creative ideas to innovate on various journal processes. If you are interested, feel free to reach out!

Accepted! Coming soon. #proteomics Matt MacDonald Stef Gallas Puig, Ph.D.🇲🇽🇫🇷🇺🇲 UMass Psychiatry and Behavioral Sciences Pitt Psychiatry

NEW! Stef Gallas Puig, Ph.D.🇲🇽🇫🇷🇺🇲 Matt MacDonald #proteomics in subjects with opioid use disorder, disrupted #circadian rhythms in #synaptic protein signaling in postmortem prefrontal cortex and nucleus accumbens in OUD Pitt Psychiatry UMass Psychiatry and Behavioral Sciences molecularpsychiatry rdcu.be/dlsEe

Check out our new review in Neuron on circadian rhythms and mood disorders!! authors.elsevier.com/a/1hxjd3BtfH5N…

Good morning #ACNP2023! Join us for our panel (JW Ybor ballroom IV) at 9 am to learn about neurodevelopmental trajectories of neuronal and synaptic proteomes with Matt MacDonald Beny Falkovich Maribel Anguiano and Genia Kozorovitskiy!

Dopplegangers spotted at the #ACNP2023 poster session mike michaelides Matt MacDonald

Intriguing paper: Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone nature.com/articles/s4138…

Multiplexing proteomics with TMT used to be plagued by low data completeness. No more. Prioritization achieves over 93% completeness across all proteins. Fig. 2: nature.com/articles/s4159…

📝Starting 2024 off with a bang 💥 I'm VERY excited to share a preprint of my dissertation work on proximity labeling proteomics and interneuron synapses. 🧠I also the show how PL and superres microscopy 🔬can reveal acute and dynamic changes that occur in the proteome

We quantified 1.498 million thermal stability measurements in cells and crude extracts treated with small molecule therapeutics and tool compounds! We interrogated on- and off-target effects to dissect direct ligand binding and indirect effects.biorxiv.org/content/10.110…

Happy to share that our paper is out Nature Communications! nature.com/articles/s4146… Congrats Lauren Rylaarsdam for leading this project, and co-authors Eleanor Pope and Jennifer Rakotomamonjy Huge thanks pacs1foundation, NINDS #PACS1syndrome #neurodevelopment #organoids #RareDisease

Congratulations 🎉

So Fun to join the session Emerging Methods to Study Psychiatric Risk Genes Across Time & Space at #MPA2024 in the charming Big Island! Fearless chairs Genia Kozorovitskiy Sofiya Hupalo + awesome speakers Matt MacDonald Arpiar Saunders, PhD Manta Ray is now my new best friend

Hey US HUPO come check out what we've been up to!

Check out the preprint by Ximena Maqueo, Lauren Rylaarsdam, Alicia Guemez-Gamboa, Matt MacDonald, Shelby Ruiz, and colleagues. biorxiv.org/content/10.110…