Congrats Nathan and team! Will be saving a photo of Warburg's dog, never know when it will come in handy.

A human metabolic map of pharmacological perturbations reveals drug modes of action go.nature.com/3CreANg

Congratulations Mattia Zampieri wow what a paper

ICYMI: "Tumor Suppressor Gene Zygosity Can Predict Therapeutic Response in Cancer" doi.org/10.1158/2159-8… A #ResearchWatch summary of a study by Mark Zucker, Maria Perry, Ed Reznik, Chaitanya Bandlamudi, and colleagues Memorial Sloan Kettering Cancer Center #LungCancer

Absolutely thrilled to receive funding through the Department of Defense's Concept Award mechanism to study mitochondrial mutations in RCC! Very thankful to Ed Reznik, Craig Thompson, and Robert Motzer MD & all collaborators and mentors for the support! Memorial Sloan Kettering Cancer Center MSK Department of Medicine

Today is the best PI day: several deadlines, and I haven't been able to accomplish anything because people keep walking in to my office and telling me stuff they just found.

Our latest work, led by Benjamin Jackson and Angela Montero Memorial Sloan Kettering Cancer Center demonstrates how intracellular metabolic gradients induce dependence on exogenous pyruvate in embryonic stem cells

We applaud Dr. Ed Reznik of Memorial Sloan Kettering Cancer Center. Ed Reznik is utilizing computational approaches to study cachexia—a syndrome affecting over 50% of cancer patients—by integrating tumor sequencing, serological data, and imaging to predict patient risk. vimeo.com/1085105337

Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto 🧵 1/ science.org/doi/10.1126/sc…

Thanks Srini!

As we all age, we accumulate mtDNA mutations, but what underlies this hockey stick pattern? See our new pre-print: we treat mtDNA SNV burden as a "trait" and use GWAS to uncover the mechanism in blood. Led by newly minted MD-PhD Rahul Gupta w/ NealeLab /labneale.bsky.social. shorturl.at/IqYY8

I'm excited to share the lab’s new paper on PDAC-associated cachexia on bioRxiv today, led by star postdoc Nikita Bhalerao, PhD Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis A 🧵 below, if you're interested... biorxiv.org/content/10.110…

Out today from ThePerryLab, our work suggesting how exposure to high fructose in pregnant mice or developing neonates directly affects neurodevelopment. In nature nature.com/articles/s4158… Memorial Sloan Kettering Cancer Center Weill Cornell Medicine funded by NIH NIH Common Fund cc: Jay Bhattacharya, MD, PhD

ThePerryLab nature Memorial Sloan Kettering Cancer Center Weill Cornell Medicine NIH NIH Common Fund Jay Bhattacharya, MD, PhD Update: Free-ish link: rdcu.be/eqx2G

Please check out our editorial just out in Nature Reviews Urology on a pragmatic approach to biomarkers for RCC! Many challenges, but with now some emerging promising biomarkers! ari hakimi Ed Reznik Robert Motzer MD Memorial Sloan Kettering Cancer Center MSK Department of Medicine nature.com/articles/s4158…