@NavAkbar @Choudhury_Lab Laurienne Edgar RDM Oxford British Heart Foundation University of Oxford Novo Nordisk Foundation Immunometabolism Network Circulation Or, ‘higher blood sugar levels reprogrammed stem cells’ if you want the condensed version of this magnum opus - congrats all 😊 inews.co.uk/news/health/hi…

After 7 years of hard work, Edgar & Akbar et al. is finally out for all to enjoy 🤓 so many congratulations & thanks to everyone involved, especially @NavAkbar, @Choudhury_Lab, British Heart Foundation and Novo Nordisk Foundation ahajournals.org/doi/abs/10.116…

Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after glucose normalization. Why glucose control alone may not be enough for #ASCVD risk reduction in #diabetes ow.ly/BXt750FvJMu #AHAJournals

A new study from Laurienne Edgar & @NavAkbar from @Choudhury_Lab shows that high levels of extracellular glucose induce trained immunity in macrophages, promoting a pro-atherosclerotic phenotype that persists even after normalization of glucose levels nature.com/articles/s4156…