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As we head to the 2025 American Diabetes Association GIP biology will be part of the conversation. Here Samms and Sloop summarize the compelling scientific story of Tirzepatide and the case for GIPR co-agonism #Diabetes #Weightloss #obesity diabetesjournals.org/diabetes/artic…

📣The Primary Care cardio-renal-metabolic philosophy of care is clear when it comes to #CVRM conditions - we have no favourites, we focus on them all 📣 See below for our updated Medscape #hacks on #CKD. We do not want to dialyse, thus we must strategize! #wholepersoncare #CKD

Significantly higher associated cardiovascular risk in people with diabetes who delay statin therapy ahajournals.org/doi/10.1161/JA… Mamas A. Mamas

Leadership 👏🏻👏🏻👏🏻

Useful review of the safety of SGLT2i dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

🩺 MASLD in T2D — but who needs fibrosis screening? 📊 In Swedish primary care (n=308): 59% had MASLD 7% had suspected advanced fibrosis 1.9% had cirrhosis ⚠️ Obesity = key driver 13% of obese had fibrosis aOR = 9.1 vs non-obese <2% if BMI <30 🧪 FIB-4/NFS = good rule-out (NPV

‘The concept of type 2 diabetes remission requires a paradigm shift towards patient-centred care..holistic disease management & evidence-based interventions aiming for sustained reduction of hyperglycaemia & adiposity, and optimisation of cardiometabolic risk factors’ 👏🏻👏🏻#CVRM

PATHWEIGH : First study of obesity intervention scaled to a population in primary care covering over 270,000 people with BMI>25!! The care delivery / implementation WORKED using existing workflows and tools and actually generated revenue!#adascisessions Implementation success!

Would love to hear more on this. #primarycareobesitycare is not a weightloss program 👏🏻👏🏻

Couldn’t agree more, whole person care is intuitive to family medicine, it is what we have been trained to do, and it is what these people deserve. #primarycareobesitycare

Delighted to join Kim Vesco to debate weight loss in pregnancy- presenting novel data from #DiGest trial funded by Diabetes UK Research. Take home message- 2-3 kg weight loss in late pregnancy in #GDM is safe & beneficial for women with BMI>25 &their babies. nature.com/articles/s4159…

Simply increasing statin doses isn’t the best solution for persistently high LDL-C. Doubling the dose only reduces LDL-C by ~6%—a diminishing return even at dramatically higher doses. Combination therapy is significantly more effective for most patients.

Are you a healthcare professional based in the UK? Are you part of a Cardiovascular Renal Metabolic Service? If yes, please help us by completing this survey (UK only): Exploring the Cardio-Renal-Metabolic Services in the UK app.onlinesurveys.jisc.ac.uk/s/leeds/cardio…

One of the most important and yet overlooked concepts in modern medicine. Obesity is not just another condition. Obesity is the central hub from which many chronic diseases emerge. Despite its significance, it remains misunderstood and marginalized in healthcare systems. If we

What is compassion? liz grant John Gillies Stewart Mercer @MDDUS_CEO RCGP Scotland SSPC Royal College of General Practitioners @BJGP SAPC Kamila Hawthorne NIHR School for Primary Care Research

🔥#ADA2025 gamechanger! 🔶 Will Mifepristone Prove A #CATALYST For Change? 🎯 The #CATALYST trial is the next evolution in personalised #T2D care. We should consider screening for #hypercortisolism in those with difficult-to-control #T2D Link in comments below 👇🏾

As some of you know, I look after many people with diabetes that have severe learning disability and are non-verbal. Today one proudly showed me a glucose trace 'in green' on their Libre app, then kissed the screen and then fist bumped me on the way out 😍 It's the most

🧬 Obesity associated with earlier, more complex MLTC (Multimorbidity) 📊 12.7 yrs follow-up: • Overweight → ↑ risk of 17 NCDs • Obesity →↑ risk of 27 NCDs • Obesity = 1.9x more complex disease trajectories 🫀 Cardiometabolic diseases hit early dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

🔎 New Definition, New Reality: Obesity Prevalence Just Jumped - - - The European Association for the Study of Obesity (EASO) introduced a new framework that redefines obesity beyond just BMI—and the impact is massive. 📊 New Data from 44,000+ U.S. Adults (NHANES 1999–2018):

The GLP-1RA/GIP agonist tirzepatide increased risk of early worsening of diabetic #retinopathy in #T2D, similar to effects of GLP-1RA treatment but conversely had a protective effect against new retinal complications in those without retinopathy Imperial College London Diabetes Centre link.springer.com/article/10.100… 🔓