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We investigated Sarilumab in patients with severe #COVID19 pneumonia and hyperinflammation (those with dismal prognosis). IL−6 blockade represents a promising therapeutic target for these patients. #COVID19FOAM @ARD_BMJ ard.bmj.com/content/early/…

Our study on @ARD_BMJ indicates that sarilumab is safe and effective in #COVID19 patients with a low percentage of consolidation at CT scan and suggests that quantification of lung consolidation is important in future trials with immunosuppressant drugs. #COVID19FOAM

More than 17000 patients were followed by the Acute Pain Service at our hospital in Milan, Italy Ospedale San Raffaele in ten years. This is the third largest case series ever published on the topic, check out this thread and the article: doi.org/10.1111/papr.1… #FOAMed #PainMedicine

Recent exposure to smoking and #COVID19? In our large case series of #COVID19 pts admitted to our hospital, we found low rates of active smokers in the ICU (3.8%) and general ward (2.2%) compared with the Italian population (25%). ccr.cicm.org.au/supplementary-… #FOAMed #COVID19FOAM

The latest SPECIAL RELEASE is now live on the Critical Care & Resuscitation Journal website! Research Letter: Recent exposure to smoking and COVID-19 ccr.cicm.org.au/supplementary-… #Covid_19 #criticalcare #coronavirus San Raffaele Anesthesia and Intensive Care

Among 99 invasively ventilated #COVID19 pts in our hospital, 75% developed acute kidney injury (46% stage 1, 21% stage 2, 33% stage 3) and 18% received CRRT. Patients with AKI had a mortality of ~40% and patients treated with CRRT >50% Article: doi.org/10.1159/000508… #FOAMcc

2/ Among invasively ventilated #COVID19 patients, AKI is very common (3 out of 4 patients) and CRRT use is common (1 in 6) and both carry a high risk of in-hospital mortality. #FOAMcc

We participated to estimate the number of adult elective operations canceled worldwide due to #COVID19: 28M 1 year to recover if and only if surgical volume will increase worldwide by 20% after a 3 months interruption thanks to government recovery plans bjssjournals.onlinelibrary.wiley.com/doi/full/10.10…

Thank you to our first 1,000 followers! You can follow us also on Facebook (facebook.com/SRAnesthesiaIC…) and Instagram (instagram.com/SRAnesthesiaICU).

The most effective timing for the initiation of renal-replacement therapy in critically ill patients with acute kidney injury was unknown before the publication of this article on the NEJM. We helped in coordinating the Italian centers. nejm.org/doi/full/10.10… #FOAMcc

do not give dexamethasone to #covid19 patients who are not receiving oxygen: mortality 17.8% vs. 14.0% of placebo #nejm Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report | NEJM nejm.org/doi/full/10.10…

We report an extraordinary increase in EMS calls/missions and ED visits in Milan during an ice storm in January 2017. 2.7k calls, 1.4k EMS missions, and ~2k trauma were managed in a single day, other peaks occurred during the Pope's visit and a heatwave. bit.ly/32uK54C

Our young colleague Stefano Fresilli will present original data on the detrimental effect of steroids in #COVID19 patients not requiring oxygen at Area Critica Italian #CriticalCare webinar/congress. Don't miss it! Free registration at areacritica.eu/webinar-2020/ Giovanni Landoni, MD

We are proud that Università Vita-Salute San Raffaele hosts SimLab, a high-fidelity Simulation Center coordinated by our Intensivist Giacomo Monti, that allows students, residents and HCPs to learn and increase their technical and non-technical skills in a protected environment. youtube.com/watch?v=eZFyIO…

Our students, residents, anesthesiologists, intensivists, cardiologists, researchers, nurses, and every healthcare provider strongly support #WorldRestartAHeart ERC - European Resuscitation Council ILCOR and #SettimanaViva Italian Resuscitation Council 1️⃣ Check 2️⃣ Call 3️⃣ Compress … and use an AED ⚡️ #ResusTwitter

Critical Care Reviews Martina Baiardo Redaelli San Raffaele Anesthesia and Intensive Care 小谷祐樹 Yuki Kotani｜集中治療医 Intensivist Alberto Zangrillo Giacomo Monti Christopher Nutt bronwen connolly Catriona Kelly Danny McAuley thanks for inviting us! we randomized 3,500 patients in >20 centers to receive continuous infusion of amino acids (vs placebo) with the aim to reduce #AKI after #cardiacsurgery #MedTwitter #FOAMed #PROTECTIONtrial pubmed.ncbi.nlm.nih.gov/36038001/

Critical Care Reviews Martina Baiardo Redaelli Giovanni Landoni, MD 小谷祐樹 Yuki Kotani｜集中治療医 Intensivist Alberto Zangrillo Giacomo Monti Christopher Nutt bronwen connolly Catriona Kelly Danny McAuley Did we find a way to protect the #kidneys and prevent #AKI ? we are happy to present 2 #RCTs in Belfast #CCR24 this year #PROTECTIONtrial #NAVIGATEtrial x.com/SRAnesthesiaIC…