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Read the original story here: science.org/doi/10.1126/sc…

Is forgetting a bug or a feature? Can you delay it and remember longer? Our 🥶COOLEST paper to date (and our most poetic abstract…) Show LOVE ❤️and please SHARE! Thread (1/N)👇 biorxiv.org/content/10.110…

science.org/doi/10.1126/sc…

Here’s the big one: In collaboration with Alf Honigmann, Shevchenko Lab, Björn Drobot and Martin Hof we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. biorxiv.org/content/10.110…

Happy to announce our preprint "EzReverse - a Web Application for Background Adjustment of Color Images" that reports a web app generated by Xinwei Song biorxiv.org/content/10.110…

Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer’s disease | Science science.org/doi/10.1126/sc…

We wrote this to wrap our heads around the role of lipids in organelle communication. This field is growing so exponentially that several new major studies were published in the meanwhile during production. Role of lipids in interorganelle communication sciencedirect.com/science/articl…

Endoplasmic reticulum–plasma membrane contact gradients direct cell migration nature.com/articles/s4158…

Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites: Developmental Cell cell.com/developmental-…

STING orchestrates the neuronal inflammatory stress response in multiple sclerosis: Cell cell.com/cell/fulltext/…

Lovely new paper and method from my old Lippincott-Schwartz Lab colleague Angelika Rambold investigating inter-organelle signaling

biorxiv.org/content/10.110…

Exciting new inroads into human biology and therapy development: Human intestinal organoids with an autologous tissue-resident immune compartment! #Gjorevski #Cabon #IHB nature Institute of Human Biology nature.com/articles/s4158…

Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes dlvr.it/TCqbRj

Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity: nature.com/articles/s4155…

Acute diacylglycerol production activates critical membrane-shaping proteins leading to mitochondrial tubulation and fission nature.com/articles/s4146…

🚀 New paper! 🧬✨Thrilled to share our latest work CDD press, pushing the boundaries of imaging inter-organelle contacts in vivo! Incredible effort by our talented postdoc Lucia Barazzuol, in collaboration with Alessio Vagnoni - now @alessiovagnoni.bsky.social and the Marisa Brini Lab. rdcu.be/efkYK🚀

Lysosomal lipid peroxidation contributes to ferroptosis induction via lysosomal membrane permeabilization nature.com/articles/s4146…

Nuclear receptor signaling regulates compartmentalized phosphatidylcholine remodeling to facilitate thermosensitive lipid droplet fusion nature.com/articles/s4146…