
Elliot Choi, MD PhD
@elliothchoi
Ophthalmology PGY-1 at UCLA @UCLASteinEye š | MD/PhD at Case Western @CWRUSOM 𩺠| BA/MS at Johns Hopkins @JohnsHopkins š§ | ģµķźµ, ģź³¼ ģ ź³µģ
ID: 1263326503388864513
21-05-2020 04:31:31
120 Tweet
1,1K Followers
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Today we report in Nature Communications the development of laboratory-evolved CBE6 cytosine base editors that offer high on-target Cā¢G-to-Tā¢A editing, virtually no Aā¢T-to-Gā¢C editing, low off-target editing, broad sequence context compatibility, and compatibility with multiple Cas





I am incredibly excited to announce the opening of the Ty Miller Lab at CWRU School of Medicine and University Hospitals in Cleveland! My lab will be dedicated to creating effective immunotherapies for brain tumor patients. Learn more at our freshly minted website - tymillerlab.org


Today we report in Nature Biomedical Engineering the eePASSIGE system, which uses evolved and engineered recombinases and prime editing to integrate large gene-sized DNA cargoes into the mammalian genome in an efficient, precise, and targeted manner. (1/13) drive.google.com/file/d/1WDMVqLā¦


We've developed a systems pharmacology-based strategy targeting GPCRs and evaluated its efficacy in multiple inherited retinal degeneration models. Proud to contribute to the study and congratulations to Henri Henri Leinonen! #ophthalmology #retina nature.com/articles/s4146ā¦

Today we report in Nature Biotechnology a system for the laboratory evolution of engineered virus-like particles (eVLPs) that enables the discovery of eVLP variants with desired properties, including improved production and delivery potency. 1/13 PDF: drive.google.com/file/d/1E6Nr86ā¦

