Enzyme Chemistry
@enzymechemistry
@SoufianTibouti thinks Nature is the ultimate chemist.
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https://www.linkedin.com/in/soufiantibouti 04-12-2019 06:28:55
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Iminium catalysis in natural Diels–Alderase by Zuodong Sun, Xin Zang, Qingyang Zhou, Ph.D Masao Ohashi, Ken Houk, Jiahai Zhou, and Yi Tang at UCLA Chem & Biochem in Nature Catalysis nature.com/articles/s4192…
Single-Enzyme Conversion of Tryptophan to Skatole and Cyanide Expands the Mechanistic Competence of Diiron Oxidases by Sanjoy Adak, Logan Calderone, August Krueger, Maria-Eirini Pandelia, Bradley Moore MooreLabSIO Scripps Institution of Oceanography in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases by P. Zeides, K. Bellmann-Sickert, Ru Zhang, C. J. Seel, V. Most, C. T. Schoeder, M. Groll & T. Gulder TaGulder Group in Nature Communications nature.com/articles/s4146…
Fungal RiPPs Side Chain Macrocyclization Catalyzed by Copper-Dependent DUF3328 #Enzyme by Chen-Yu Chiang, Masao Ohashi (Ph.D Masao Ohashi), and Yi Tang (Yi Tang) at UCLA Chem & Biochem in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Concise #Biosynthesis of Antifungal Papulacandins by Chao Yu, Niandi Zhang, Jinmei Li, Mingxin Zheng, Meihui Zhao, Ling-Yan Wang, Zhiqiang An, Gerald F. Bills, and Zhuan Zhang in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Intermolecular 1,2,4-Thiadiazole Synthesis Enabled by #Enzymatic Halide Recycling w/ Vanadium-Dependent Haloperoxidases by Manik Sharma, Cameron Pascoe, Stacey Jones, Sophia Barthel, Katherine Davis The Davis Lab, and Kyle Biegasiewicz Kyle F. Biegasiewicz in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Pyrroline Ring Assembly via N-Prenylation and Oxidative Carbocyclization during #Biosynthesis of Aeruginosin Derivatives by Wenhe Zhang, Richiro Ushimaru, Masahiro Kanaida, and Ikuro Abe in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Non-Canonical Type II Terpene #Cyclases Deliver Rare Terpenoid Architectures by Rose M. McLellan (Dr Rose McLellan), Daniel Berry, Rosannah C. Cameron, and Emily J. Parker at Ferrier Research Institute in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Mechanism of Unexpected In-Trans Post-PKS Polyketide Reduction in Cochliodone #Biosynthesis by Christopher Sarmales-Murga, Michio Sato, Motoki Kosaka, Fumito Akaoka, and Kenji Watanabe in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Mechanistic Characterization of Diterpene Synthase Pairs for Tricyclic Diterpenes from Cyanobacteria by Jiayi Yu, Taro Shiraishi, Kizerbo Taizoumbe, Yusaku Karasuno, Ayako Yoshida, Makoto Nishiyama, Jeroen Dickschat, Tomohisa Kuzuyama_Lab in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Quantum Coulombic Interactions Mediate Free Radical Control in Radical SAM Viperin/RSAD2 by M. Hossein Khalilian and Gino A. DiLabio Gino DiLabio in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Exquisite Complex Reaction Cascade in the Natural 1,2,4-Triazine Assembly by Yiyuan Cheng, Haoran Pang, and Wenjun Zhang in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Catalytic Enantioselective Smiles Rearrangement Enabled by the Directed Evolution of P450 Radical Aryl Migratases by Wenzhen Fu, Katherina Murcek, Jasper Chen, An Liu, Yunlong Zhao, Peng Liu (Peng Liu Group), and Yang Yang (Yang Yang) in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent #Enzymes by Shunsuke Kato, Shuto Fujisawa, Yuto Adachi, Mitsuhiro Bandai, Yutaro Mori, Seiji Mori, Tomokazu Shirai, and Takashi Hayashi in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Synergistic #Photoenzymatic Anti-Markovnikov Hydroarylation of Olefins via Heteroaryl Radical Intermediates by Prasun Mukherjee, Zayed Alassad زايد الأسد, and Todd K. Hyster at Princeton Chemistry in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
C–C Bond Cleavage in the Late-Stage #Biosynthesis of Huperzine Alkaloids Occurs via #Enzymatic Retro-Aza-Prins Reaction by Stefan E. Payer, Mario Prejanò, Philipp Kögl, Tamara Reiter, Eva-Maria Pferschy-Wenzig, Fahmi Himo, Wolfgang Kroutil in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
#Photobiocatalytic Enantioselective Benzylic C(sp3)–H Acylation by Yen-Chu Lu, Ronald Adukure, Satyajit Roy, Derek Chien, Matthew McGill, Sarthi Polara, Andrés Cisneros, Karl Scheidt, Rudi Fasan Lab at UT Austin Chemistry in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
Discovery of acylsulfenic acid-featuring natural product sulfenicin & characterization of its #biosynthesis by Xue, Zou, Qiu, Lv, Madden, Xu, Lian, Pulliam, Ethan Older, Hou, Campbell, Tristan de Rond, Awakawa, Yuan, Bradley Moore in Scripps Institution of Oceanography, Li nature.com/articles/s4155…
Structural Basis for Dehydrogenase/Reductase-Catalyzed Reductive Cyclization in Polycyclic Tetramate Macrolactam #Biosynthesis by Xiangqian Xie,Fan Li, Yanxin Mu, Mengyao Lu, Jie Luo, Haoxin Wang, Yuemao Shen, Liangcheng Du, Deyu Zhu, Yaoyao Li in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…
