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Very pleased to share our latest review on pathogenesis and biomarkers of prognosis of #MOGAD by first author Jane Andersen. sciencedirect.com/science/articl… Have a look at the figures! The Sumaira Foundation The MOG Project Brain & Mind Centre Sydney Health

Using high-throughput PhIP-Seq, we identified NPAS4-IgG, a novel autoantibody in CSF of antibody-negative autoimmune limbic encephalitis & additional AK5-IgG cases, highlighting PhIP-Seq’s role in uncovering new autoimmune biomarkers#AutoimmuneEncephalitis pubmed.ncbi.nlm.nih.gov/40133514/

We are proud of our past chief! Congratulations Dr. Syc!! ⭐️

Congratulations to Dr. Amit Bar-Or, MD for winning the John Dystel Prize for Multiple Sclerosis Research for numerous publications on diagnosis, treatment, and the underlying immunopathologic mechanisms of MS. multiplesclerosisnewstoday.com/news-posts/202…

Although neuromyelitis optica spectrum disorder (NMOSD) has been reported to be more common in Asian people, this study in Southern California actually found it is most common in black people (incidence around 100,000:1) pubmed.ncbi.nlm.nih.gov/40156304/

Autoimmune encephalitis: recovery, residual symptoms and predictors of long-term sequelae jnnp.bmj.com/content/early/… Smathorn Thakolwiboon

If you are attending the American Academy of Neurology meeting, don’t miss the opportunity to meet our Mayo Clinic Neuro experts during the lunch hour from Sunday to Tuesday at booth #1613 (in red). It is such an honor to be among these giants promoting our Mayo Clinic Labs. Please come say hi! 😅

I am so excited (and honored) to serve as President-Elect of the AAN alongside @nsanar and this talented team of leaders, with the best staff and volunteers in the business, and continuing the AAN’s work on behalf of neurologists and our patients Let’s gooooo! #AANAM

#CASPR2-#antibody diseases are provide clues to mechanisms of autoantigen-specific tolerance Here - in Science Advances - we show how central and peripheral B cell tolerance licences pathogenic CASPR2 antibody generation. science.org/doi/10.1126/sc… More below 👇🏿

Falls are a common problem in people with MS, can we use patient reported outcomes and gait testing to identify those at risk? Here we present a clinical scoring tool for fall risk assessment. journals.sagepub.com/doi/10.1177/20…

Our new paper is finally out! A terrific joint effort to advance our understanding of T cell mediated neurodegeneration in AE ! “Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens” link.springer.com/article/10.100…

Congratulations to Dr. Jones (Neuromuscular fellow) for his recent publication in Neurology, “False Positive Acetylcholine Receptor Antibody Testing in Clinical Practice.” #ScholarlySunday #MayoNeurology #NeurologyFellowships

Delighted to share Cacciaguerra et al study ➡️ MRI guidelines in MS recommend 2 sagittal-T2 spine images but axial is optional ➡️ Here, axial-T2 found 2x more lesions vs sagittal ➡️ Thus, future guidelines should recommend both sagittal & axial images👇 link.springer.com/article/10.100…

Mayo Clinic has a long tradition of physician training, and I’m happy to share that I’ve been appointed Dean of the Mayo Clinic School of Graduate Medical Education Future physicians will enter an exciting and challenging profession. They need to be prepared for the next 30

Congrats to Dr. Aboseif (MS fellow) on his recent publication in Neurology, “Cytokine, chemokine, and neurofilament light chain signatures in anti-LGI-1 encephalitis.” Don’t miss his 4-part Neurology Minute podcast series exploring the findings! 🧠 🎙️ neurology.org/doi/abs/10.121…

Risk of False Acetylcholine Receptor Autoantibody Positivity by Radioimmunoprecipitation Assay in Clinical Practice hubs.ly/Q03kXGrM0

Delighted to share Dinoto et al study on late onset MOGAD (50 yrs or more) ➡️ Accounts for 25% of MOGAD ➡️ Optic neuritis dominates & often misdiagnosed as ischemic (NAION or temporal arteritis) ➡️ Outcomes favorable & similar to other age groups 👇 neurology.org/doi/10.1212/WN…

🔱Do you know in which conditions the trident sign appears on spinal MRI? 🙃And what if I told you this patient showed a reversed trident sign, with ventral rather than dorsal enhancement, along with subacute paraparesis and urinary retention? 👉What would you suspect?

If you haven't already, mark your calendars! We're so excited to host the U.S. #MOGAD Patient Summit on Saturday, August 16th in collaboration with Mayo Clinic. Plan on learning the latest information on this disease, its diagnosis, management & treatment from the clinicians

May it help interested clinicians and their patients.