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Join the EFMC Best Practices Working Group to learn about chemical probes, phenotypic drug discovery, and hit generation. Access free webinars, articles, and slide decks for personal or educational use. 🔗 buff.ly/3PV0HuN

📰 EFMC Literature Spotlight - October 2023 📰 📌 "Development of Multivalent Conjugates with a Single Non-Canonical Amino Acid" ChemBioChem (2023). 🔗 Read more on: buff.ly/3RNB0xx #EFMCLiteratureSpotlight #ChemBio #MedChem

EFMC strongly condemns the recent terrorist attacks made against the state of Israel, and express its support to the scientific community and to the population impacted by these dramatic events. See full statement on EFMC website efmc.info/info/efmc%20me…

The final version is finally out in today’s issue of J. Med. Chem. (ACS Publications Bio & Med Chem Content). Congrats again to all the authors. EpigeneticMedChemLab Sandro Cosconati Sabrina Castellano UCLA Chem & Biochem City of Hope pubs.acs.org/doi/10.1021/ac…

Farewell pizza party to say goodbye to Maxi (Manfred Jung lab), who is going to come back to Freiburg at the end of the week. See you soon, Maxi, it was a pleasure to host you in the EpigeneticMedChemLab!

Proud to be part of the EFMC #MedChemBioConversations series! DCF-SCI

DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8 (G. Sbardella et al.) Gianluca Sbardella Giuliana Sarno AlessandraFeoli Sabrina Castellano EpigeneticMedChemLab Università Salerno onlinelibrary.wiley.com/doi/10.1002/cb…

Amazing work! Congratulations to Nuno and all the authors of the MaulideGroup involved (especially Giulia Iannelli, of course, but I’m biased 😊)! EpigeneticMedChemLab

It is a pleasure and honor to start my term as co-Chair of ChemMedChem Editorial Board, together with Anna and Sangyong. It will be a great adventure. DCF-SCI EFMC EFMC Young Scientists Network Chemistry Europe

The new issue of ChemMedChem is out (…mistry-europe.onlinelibrary.wiley.com/toc/18607187/2…), featuring on the front cover the generation of molecular counterfactuals (CFs) for compound activity predictions using machine learning, by Alec Lamens and Jurgen Bajorath (doi.org/10.1002/cmdc.2…).

Structure-Based Design of AG-946, a Pyruvate Kinase Activator (Lenny Dang et al.) #openaccess onlinelibrary.wiley.com/doi/10.1002/cm…

Congratulations, Giulia Iannelli!

Hit-to-Lead in drug discovery! The new chapter of the EFMC Best Practices in Med Chem series has just been released. As usual, the material is freely accessible for personal use or for use in further training or teaching material efmc.info/hit-to-lead

Check also the previous chapters on the EFMC website (efmc.info/best-practices) and the corresponding viewpoint articles in ChemMedChem: …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm… …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm… …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm…

Another great idea of the #MedChemFrontiers24 programme is a Focus on Early Career Investigators. The session is chaired by Rita Petracca, introducing it with a super-nice metaphor of the “rolling disco”. Well done, Rita! EFMC EFMC Young Scientists Network ACS Division of Medicinal Chemistry EpigeneticMedChemLab

A very interesting ChemMedChem editorial by Donald Weaver reminds of the underappreciation of the role of medicinal chemistry in the health and socioeconomic well-being of humankind, even if drugs are designed, created and invented by medicinal chemists. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm…

Had an amazing time last week at #MedChemFrontiers24 by EFMC & ACS Division of Medicinal Chemistry. Outstanding scientific contributions, food for thought, meeting old and new friends and a great reunion of former members of EpigeneticMedChemLab, Rita Petracca, Filomena Saulino, Andrea Trezza. 😊

EpigeneticMedChemLab new photoreactor with Kessil high power LED lamps just assembled and already at work. Can’t wait to see the reaction outcomes!

The EpigeneticMedChemLab will be present, as usual, this time with 4 attendees from the group. Enjoy ESMEC and Urbino, Ben, Ida, Rosy and Giuliana Sarno!

Our recent work is now available as an Early View ChemMedChem article. Congratulations to all the co-authors!