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Sedation practices in cardiac patients are evolving. What are the safety outcomes of dexmedetomidine use in a modern CICU population? Find out in our Michigan Cardiology U-M Health Frankel CVC U-M College of Pharmacy study #EHJACVC w/excellent work by my all-star colleagues. bit.ly/2QB2TIu

Back with another CardioNerds #CNCR Tweetorial, this time with amazing WeAreNUHeart fellows! See the full case below and some major points in the💯Karan Desai MD FACC CN5 graphic⬇️: cardionerds.com/56-case-report… Today we’re talking a LITTLE about genetic counseling in cardiomyopathy (CM)

Intronic #CRISPR Repair in a Preclinical Model of #Noonan Syndrome-Associated Cardiomyopathy. Learn more: ow.ly/71Zl50Brcnf #AHAJournals @moenklein Lukas Cyganek Uni Göttingen DZHK Germany

Awesome case w/ Nicole Martin Bhave, MD, FACC, FASE and muazzum shah at echo conference! A patient with remote TAA repair and mild AI presents (after previously being lost to follow up) with cough with blood tinged sputum, back pain, and dyspnea for 3 days (written consent obtained, details changed)

**VALVE CASE OF THE WEEK** OK, this starts off about valves...but then isn't really about valves...but it's the broader educational point (which is relevant to valves) that I want to make this week...no poll I'm afraid, but as always, comments encouraged! 😁 BHVS

Our new study using #ISIC on #SuPAR and incidence of COVID19 related #AKI - new potential use for #SuPAR in risk stratification in COVID19 Salim S. Hayek, MD Michigan Cardiology U-M Health Frankel CVC jasn.asnjournals.org/content/early/…

Check out this interesting case hosted by CardioNerds and presented by Michigan Cardiology Fellows Apu Chakrabarti, @JessicaGuidiMD, and Akanksha Deshmukh! With teaching points and insights by @D_Sukul and @KEagleMD! 〽️ #GoBlue

Excited to share our review in Heart_BMJ discussing Multimodality Cardiovascular Imaging, strengths and limitations of different imaging modalities, and how it can be effectively delivered with Marcelo Di Carli and Ron Blankstein Brigham and Women’s Cardiovascular Imaging Program heart.bmj.com/content/early/…

Look! Our paper on SuPAR predicting AKI in COVID-19 was voted the second biggest nephrology story by Nephrology Journal Club! nephjc.com/news/2021/1/8/… Salim S. Hayek, MD Cardiac Biomarkers Lab

Check out our article on using micro-randomized trials (MRTs) for the evaluation of Just-in-Time Adaptive Interventions (JITAIs). Really excited to help others learn about this novel study design! ahajournals.org/doi/10.1161/CI… Circ: CQO Brahmajee Nallamothu Elizabeth Jackson

Remote monitoring is the gold standard of care for patients with CIEDs, but current processes are laborious and error-prone. Check out our proposal to Transform Cardiac Device Care for the #FCVCInnovation Challenge! #EPeeps youtu.be/4DljYLChKAs U-M Health Frankel CVC Michigan Cardiology

Safe on Mars. go.nasa.gov/3axlXCf

Excited to present our work on mortality after first infection in LVAD patients at virtual #ISHLT2021. Couldn't have done it without Guangyu Yang, @DLikosky Dr. Francis Pagani, Carol Chenoweth, Preeti Malani mike fetters Michael Pienta, Lula Cabrera and the rest of the team!

Fellowship family portrait! Melinda Davis @mshetts1 Marty Tam Eric Smith Richard L. Weinberg Andrea Dooley Thompson, MD/PhD @JessicaGuidiMD @S2beri @Rabel2016 Tariq Azam, MD FACC FACP Raymond Y. Yeow

Our paper on “The genetic architecture of Plakophilin 2 cardiomyopathy” is now online at Genetics in Medicine. Please check it out (and/or read the thread below) at rdcu.be/cmqCE ! 1/n

Thread/ Check out our article on ACC.org American College of Cardiology discussing #mavacamten induced structural changes in #HCM - we also show example of #echofirst images over 144 weeks of treatment acc.org/latest-in-card… Starting with the quick takes #cardiotwitter

Conference Q&A

Excited to share our work on iPSC-derived 2D cardiac muscle bundles. Accessible and reproducible contractile assessment, insights on cardiac development, disease modeling. Read Nature Communications rdcu.be/cz3pD Baker Lab Dr. Lori L. Isom yuweiwu_imb U-M Health Frankel CVC

The first set of #ESCGuidelines for cardiomyopathy. Fantastic to see standing room only at #ESCCongress2023 as guidelines aim to increase CM awareness outside the subspecialty #CardioGen clinic academic.oup.com/eurheartj/adva…

Low penetrance sarcomere variants (LowSVs) contribute to mild HCM alone but increase severity with high-risk variants. Neal Lakdawala James Ware Anjali Owens A/Prof Jodie Ingles @S2beri @sday_hcm Sean Zheng Adam Helms ahajournals.org/doi/abs/10.116…