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New in Small Molecule Therapeutics: Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification brnw.ch/21wS10R

#PallOnc trial on #ACP in JCO Oncology Practice ✨Facilitated 👪 #ACP ⬆️ engagment and #ACD vs patient 🧑‍🦱 directed #ACP. ✨Both groups saw gains, but facilitated prove many need help 🤝 🔗: ascopubs.org/doi/10.1200/OP… OncoAlert🚨 ASCO PallOnc Community of Practice #OncoAlertAF Emre Yekedüz Fadi Haddad, MD

The OncoAlert🚨Newsletter, EVERY WEEK! This week Covering April 11-17, 2025 REGISTER at OncoAlert360.com OR oncoalert.m-pages.com/nhMpwe/oncoale… Discussing ✅TALAPRO2 in #ProstateCancer ✅SBRT☢️ & IO in #KidneyCancer ✅ Challenges in #SCLC heterogeneity &Plasticity🫁

🧫CAR T cell therapies in gastrointestinal cancers Nature Reviews Gastroenterology & Hepatology ✅Ongoing trials for CRC, pancreatic, gastric, esophageal cancers ✅Challenges and strategies 👉doi.org/10.1038/s41575… OncoAlert #cancer #oncology #MedX

Congrats for the study! Liver transpantation in oncology is roading speedly ✅ deniz balci

Weekly round up OncoAlert is the easiest way to stay update! Registration👇

🧬Is HER2 amplification prognostic for OS in advanced biliary tract cancer❓ JCO Precision Oncology ❌No mOS: 17.7 v 16.9 mo HR: 0.95 (0.65-1.40) ✅But Yes if HER2 targeted therapy mOS: 24.3 v 12.1 mo HR:0.39 (0.23-0.82) 👉doi.org/10.1200/PO-24-… ASCO OncoAlert #cancer #oncology

📰Extra! Extra!📰 OncoAlert Newsletter is live #GIonc studies include: 🌟 Pemigatinib 🎯in Advanced #Cholangiocarcinoma #hpbcsm 🌟#HIMALAYA 🏔️ tremelimumab+ durvalumab in #HCC Never miss an edition by signing up here: OncoAlert360.com OR oncoalert.m-pages.com/nhMpwe/oncoale……

📈HCC in primary sclerosing cholangitis HEPATOLOGY Journal ✅Relatively rare 🚨Risk: Cirrhosis and >50 years-old ➡️Might help for surveillance strategy and at differntial diagnosis 👉10.1097/HEP.0000000000001351 OncoAlert #cancer #oncology #liver

Terapias dirigidas a fusiones FGFR2 en vía biliar ‼️Dirigido al dominio extracelular ‼️Sinergia con inhibidores de FGFR ‼️Actividad contra las mutaciones del dominio quinasa #cholangiocarcinoma Asociación de Tumores de Vías Biliares Grupo Español de Tratamiento de Tumores Digestivos

CCA, CRC and HCC screening in patients with PSC 👇

🩸Patients with AF ➡️ anticoagulation ➡️bleeding ➡️ new cancer diagnosis❓ Circulation 🚨4.9% diagnosed with cancer within the next 2 years 🚨Risk, HR: 4.0 (95% CI, 3.8–4.3) ‼️Cancer diagnosis risk in bleeding site: HRs: GI: 15.4; GU: 11.8; respiratory: 10.1 ❓Earlier diagnosis:

Go go go, future leaders of oncology! Thrilled to see this important contribution from our young colleagues on early-onset colorectal cancer just published in International Journal of Cancer. Stage-specific data on localized and synchronous metastatic disease—because young CRC

Erman Akkus keys🕵🏻 HER2 amplification for target therapy in advanced biliary tract cancer 🧬🎯 #cholangiocarcinoma Asociación de Tumores de Vías Biliares Grupo Español de Tratamiento de Tumores Digestivos SAOM GEODA

🧬European screening platform for EORTC clinical trials in advanced CRC "SPECTAcolor" ESMO - Eur. Oncology GI Oncology ➡️The simple κ coefficient for the agreement between local and central testing: ✅0.82-0.95 for KRAS, NRAS, and BRAF 🚨But 0.55 for MSI-H ❗️ 👉doi.org/10.1016/j.esmo…

Artículo original El análisis por deep learning de imágenes por resonancia magnética detecta con precisión el colangiocarcinoma perihilar en etapa temprana en pacientes con colangiopatía esclerosante primaria Singh et al. #LiverX tinyurl.com/5n7jy7vc

📚Korea, Japan, Europe, and the United States: Why are guidelines for gastric cancer different? ✅Key differences 👇 doi.org/10.1007/s10120… ESMO - Eur. Oncology ASCO OncoAlert #cancer #oncology #gastric #MedX

CONSORT 2025 statement: updated guideline for reporting randomized trials | Nature Medicine nature.com/articles/s4159…