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Our latest manuscript on the Microbiome Utrecht Infant Study (MUIS) is now published in ⁦Nature Communications⁩ ‘Mode of delivery modulates the intestinal microbiota and impacts the response to vaccination’ (open access). nature.com/articles/s4146…

The dynamic lung microbiome in health and disease Natalini, Singh & Segal review the role of the lung microbiome in health and disease and discuss future work that is needed to produce novel diagnostic and therapeutic tools aimed at improving lung health rdcu.be/cZQ4d

Out today in Science Magazine, our paper on cross-trait assortative mating and why estimates of genetic correlations (i.e. shared genetic effects on phenotypes) are likely inflated. See this thread from the preprint for an overview of the idea and results

As genetics/genomics becomes a part of everyday life, the importance of genetic literacy grows. Learn more about where things stand in the latest paper from @girlscientist & colleagues cell.com/ajhg/fulltext/…

A ThoraxBMJ editorial highlights our recent work on the role of genetic ancestry on asthma exacerbation risk in Hispanics/Latinos 🙌🙌 thorax.bmj.com/content/early/…

What are the advances in asthma exacerbations from the genomic, epigenetic and transcriptomic perspectives? See below the word cloud from our recent literature review published at #JIACI from SEAIC jiaci.org/ahead-of-print…

My son, who is color blind, sent me this resource. It really is worth keeping folks like him in mind when you make your figures. davidmathlogic.com/colorblind/#%2…

The implementation of polygenic scores holds great promise for personalized medicine but challenges remain if everyone is to benefit. Check out the new ASHG guidance on "Addressing the challenges of polygenic scores in human genetic research" published today AJHG

#Alergólogos del #HUC publican un estudio sobre pacientes asmáticos graves tratados con #fármacosbiológicos www3.gobiernodecanarias.org/noticias?p=998… SEAIC Sanidad Gobcan Medicos Tenerife

Ya están aquí las XVI Jornadas de Genética de la Universidad de La Laguna. Nos vemos el próximo 27 de diciembre en el Aula 1 de la Sección de Biología (también online). La inscripción será a través del siguiente enlace: forms.gle/VuwatoqsFod9g3… Te esperamos. Hasta pronto!

Ya estamos de lleno con la organización de las XVI Jornadas de Genética de la ULL. Será el martes 27. Aula 1 de Biología, en sesión presencial y online. Anímate a estar con nosotros ese día y ver la evolución de nuestros ex-alumnos en su carrera científica forms.gle/VuwatoqsFod9g3…

You'll want to check out Jiacheng Miao's new paper if your work involves gene-environment interaction. This is our best GxE work so far. We introduce a statistical framework named PIGEON to reimagine how GxE studies could and should unfold. biorxiv.org/content/10.110…

🎄🎁Recibimos la Navidad con nuestro árbol decorado por los jóvenes investigadores del Área de Genética con materiales reciclados 🌟🎄Universidad de La Laguna Genomics and Health Lab (ULL) Paleogenomics Lab at ULL

Ya arrancaron las XVI Jornadas de Genética. Ya habló Sara sobre ADN antiguo procedente de restos del siglo XVI encontrados en la Isleta. Ahora expone Carlos sobre epigenoma y asma.

XVI Jornadas de Genética ULL. Tras un breve descanso seguimos con la charla de Natalia Hdez Pacheco, puntuaciones poligénicas y enfermedades respiratorias

Our study 'Lung function in young adults born small for gestational age at term', is now out! onlinelibrary.wiley.com/doi/10.1111/re…

The pitfalls of using polygenic risk scores in population screening while ignoring rare pathogenic variants. Via Nature Reviews Genetics nature.com/articles/s4157… Robert C. Green Paul Lacaze

New! Dylan Duchen et al. underscore the importance of choosing appropriate controls when studying outcomes dependent on environmental exposures #GWAS bit.ly/3QNZAM9

When I teach Principal Component Analysis (PCA), I use my interactive dashboard to engage my students. They can observe how, through an orthogonal transformation (rotation) of a two-feature dataset, the variance of the data projected onto one of the components can be maximized.

📢Excited to share our comprehensive review led by Esther HL on gene-environment interactions. Within, you'll find: 🛠️Summary of current methods by underlying hypothesis 🗺️Framework for considerate epidemiological modeling 🗣️Call for greater contextual diversity needed for GxE