Some words of wisdom from this year's chemistry laureate David Baker, whose work has made it possible to design new proteins from scratch. Read more and join us on tomorrow 8 December to hear his Nobel Prize lecture: nobelprize.org/prizes/chemist…

Postdoc position available. Please repost🙏

Excited to announce our latest review on #insulin -IGF receptor signaling! Nature Reviews Molecular Cell Biology rdcu.be/d9mvD nature.com/articles/s4158…

”There are a lot of cases where the really important, critical suggestions come because one person on one project suggests something to another person working on another project. It’s a really important aspect of it, to keep a collegial environment where people are comfortable

Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.

Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs Biochemistry & Molecular Biophysics reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online Cell! sciencedirect.com/science/articl…

Online Now: Tuning insulin receptor signaling using de novo-designed agonists dlvr.it/TNfGjj

Where do cancers start? In the liver, not all cells are the same. The liver is divided into 3 “zones,” and each specializes in different metabolic tasks. We show in @Science that where a mutation occurs in a liver lobule can determine a cell’s fate. science.org/doi/10.1126/sc… (1/9)

Tuning insulin receptor signaling using de novo-designed agonists dlvr.it/TP6vLk

📢 Our Dept. of Systems Biology Columbia University has an open tenure-track Assistant Professor position in the broad area of quantitative biology. Come join our awesome department in NYC! Please circulate. Apply: apply.interfolio.com/177622 Suggested deadline: Dec 15, 2025. Columbia Systems Biology

A new horizon unfolding for insulin signaling in health and disease dlvr.it/TPRqlh

How is #insulin production affected in residual beta cells in type 1 #diabetes? Préfontaine et al show unexpectedly that stressed senescent beta cells continue to produce mature insulin in the context of type 1 diabetes #DiabetesResearch #T1D #Islets link.springer.com/article/10.100… 🔓