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Thrilled to share that the PITT pathway is now online nature. rdcu.be/cU85m. We identified ER-lysosomal membrane contacts and subsequent lysosomal lipid transfer as an essential mechanism for rapid lysosomal repair. University of Pittsburgh Aging Institute at the University of Pittsburgh PittDeptofMed UPMC

Excited to share this: a new #cellline model to study #prostatecancer development! Happy to have contributed to this collaboration with Tapio Visakorpi Nykter Lab. Huge congrats to PhD student Konsta Kukkonen for his first thesis publication! A thread. doi.org/10.1530/ERC-22…

Great update on the field of LYTACs, or lysosome-targeting chimeras, and autophagy degraders.

Ian Mills Ian Mills is running this month to raise awareness around prostate cancer and raise money to fund research. Please support if you can. The Patrick G Johnston Centre for Cancer Research Prostate Cancer UK

Sometimes working on basic science has implications for people’s life. Studying intracellular lipid trafficking we have stumbled upon a group of individuals affected by neurodevelopmental syndrome and bearing mutations in CERT1 jci.org/articles/view/…

Please come and talk to us about cancer research Balmoral Show ! The Patrick G Johnston Centre for Cancer Research #scienceoutreach

Congratulations to James Holloway who passed his PhD viva today! I’m proud to have supervised you during these years!

While lipid droplets are generally known as lipid storage organelles, the primary function for lipid droplet biogenesis may be for alleviating endoplasmic reticulum stress. Check out our latest review for details.

#MembraneTrafficking online seminars are back with a stellar lineup for the fall season! Join Fèlix Campelo Francesca Bottanelli and me for a whole lot of great science.

Excited to share our latest work on prostate cancer and our first on membrane contact sites. We imaged for the first time ER-mitochondria contact sites in tumour and explant tissue samples. Great collaboration with the Butler lab Lisa Butler frontiersin.org/articles/10.33…

The launch is underway! PGJCCR's brand new #ProstateCancer Centre of Excellence is Ireland's first independent prostate cancer research centre. We'll be sharing some of their research through the week so watch this space! qub.ac.uk/News/Allnews/2…

Delighted that our paper is out in CDD press with James, Richard Turkington & dlongley. We present a new regulatory role for the E3 Ub ligase Itch in apoptosis and mitochondrial cholesterol supply. rdcu.be/dvRnh The Patrick G Johnston Centre for Cancer Research #apoptosis #mitochondria #cholesterol #ubiquitin

✨Original Article✨ ⭐StarD7 deficiency switches on #glycolysis & promotes #mitophagy flux in C2C12 myoblasts⭐ ✍️By Genti-Raimondi, Zorzano et al UNC CONICET Dialoga CIBICI IDIBGI Institut d'Investigació Biomèdica de Girona @ciberdem IRB Barcelona Universitat de Barcelona ➡️buff.ly/3vJVle5 #lipiddroplet

For all lovers of cancer metabolism, please join us in Adelaide, Australia, for ACMM2024! Abstract deadline April 1, plenty of opportunities for talks for students/ECRs, and interactions with our international faculty. See you May 15-17- website details 👇

#MembraneTrafficking seminars are back in 2024! Join Fèlix Campelo Francesca Bottanelli and me next week for two exciting talks. Looking forward to seeing you membrane enthusiasts again! Feb 29, 5.00pm CET, 11.00am ET

📢 What role do novel therapeutics that block persistent androgen receptor signalling have in castrate-resistant #prostatecancer? Congrats Adam Sharp and team The ICR and beyond, publishing in Molecular Cancer Therapeutics Grab a ☕and read: bit.ly/3IGJr7U

The review that we wrote together with Ian Mills and our MSc student Grace has been published by J Cell Science. Please read it if you are interested in Adaptations of membrane trafficking in cancer biology! The Patrick G Johnston Centre for Cancer Research QUB MHLS Faculty

MOST interesting!! : Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum nature.com/articles/s4155…

Please RT and help us get the word out. Scott Dixon @sjd956 and I are co-organizing the first FASEB #Ferroptosis conference this summer! Awesome line up of speakers and room for additional short talks! Save the date & come join us July 27 - 31, 2025! 🤩events.faseb.org/event/11797f9e…