
ExM
@exmicroscopy
ID: 1060633945493012480
08-11-2018 20:43:33
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44 Followers
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We plan to distribute some trifunctional anchors used in this work for free 😁, after official publication!! biorxiv.org/content/10.110… Let us know if you wanna try out this brighter, high labeling efficiency, 5-nm resolution LR-ExM. Easy to use! Ian Seiple






LR-ExM using tri-functional anchors enhances #expansionmicroscopy labeling efficiency to resolve molecular-scale features in cells. Work by Xiaoyu Shi in collaboration with Ian Seiple lab. biorxiv.org/cgi/content/sh…

It is amazing to see Tri-functional linkers for expansion microscopy in two recent preprints on July 1 biorxiv.org/content/10.110… (Huang and Seiple labs, UCSF Bo Huang Lab Ian Seiple Xiaoyu Shi) and on July 8 biorxiv.org/content/10.110… (Hofkens lab, KULeuve Marisa 🔬🧬👩🏼🔬 Rob Neely)




#Expansionmicroscopy helps see heat shock proteins (Timmerman, Baldwin, and Benesch labs, biorxiv.org/content/10.110…), the pathogen Chlamydia trachomatis (Rudel lab, frontiersin.org/articles/10.33…), and a Drosophila larva (Preibisch lab, nature.com/articles/s4159…). From the last paper: