🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Was excited to determine the in situ clathrin structure for this project! That’s my first EM-structure upload to EMDB. Can I tell my mom I am a structural biologist now? 😄 #cryoET

#MINFLUX will be one of the most useful microscopy tools in the coming decades:

Gregor Mendel is so much cooler, and his life so much richer, than your high school biology class might suggest. Here are 12 things I recently learned about Mendel. 1. After his death, thousands of his pages (filled with data) were destroyed. Nobody knows why this happened.

More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have had a highly cited paper, changed their research topic between their #PhD and postdoc, or moved abroad after receiving their doctorate. pnas.org/doi/10.1073/pn…

Nine years and 3 million pages of script: Acting in a video game epic bbc.in/4gxPbj6

CryoCrane, a visualization tool for cryo-EM screening data, aims to provide an intuitive way to visualize micrographs and to speed up data analysis. Universität Potsdam Structural Biology Communications IUCr #CryoEM #SampleOptimization #GridScreening doi.org/10.1107/S20532…

The John Briggs, alongside teams from CIID_Heidelberg and YaleMicroPath, uncover the elusive role of the #HIV-1 component SP2. Detailed 3D views of virus particles by #cryoEM show how SP2 helps the virus matrix to mature. ❕Read the paper nature: nature.com/articles/s4158…

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from Margot Riggi :

Whats the best slit width for your energy filter? ⁦Max Clabbers⁩ systematically tested the settings. The results may surprise you... Characterization of energy filtering slit widths for MicroED data collection | bioRxiv biorxiv.org/content/10.110…

Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in Cell cell.com/cell/fulltext/… . What’s new?

Hey ChimeraX users! ChimeraX-CliX now supports color preview, quick menubar/toolbar search, and many other powerful features to support you. If you are interested in, please download the latest version -> cxtoolshed.rbvi.ucsf.edu/apps/chimeraxc…

LigandMPNN is a deep-learning-based protein sequence design method that can explicitly model all nonprotein components of biomolecular systems. nature.com/articles/s4159…

Did quantum mechanics for protein structures sneak up on everyone else this past year, or was it just me? Recently-impossible, 🔥protein-scale🔥 quantum accuracy is now feasible with AI-native, whole-protein quantum refinement

CodonTransformer: a multispecies codon optimizer using context-aware neural networks Scientists looking to produce proteins in new host organisms often face challenges in adjusting DNA sequences to match the host’s translation preferences. This customization, known as codon

Introducing ATOMICA 💫 A model to universally represent molecular interactions (for proteins, nucleic acids, small molecules, and ions) at an all-atom scale 🧵