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Thrilled to share our latest work published in #NatureCancer! 🥳We uncover the metabolic vulnerability of and develop novel therapy for advanced prostate cancer with SPOP and CHD1 defects! Grateful to my amazing team, collaborators, and supporters! 🙏MD Anderson Cancer Center Read it here:

Dal 19 al 21 maggio torna Pint of Science, il festival che porta la scienza dentro i bar. Ricercatori e ricercatrici presenteranno progetti e scoperte direttamente al pubblico, raccontando quale impatto avranno sul futuro. Leggi il programma completo: pintofscience.it/events/trento

Exciting news! Our commentary is finally out, cudos to the team at EURAC (BZ) and CIBIO (TN) 👏 Human mitochondrial DNA in public metagenomes: Opportunity or privacy threat? cell.com/cell/fulltext/…

Peak analysis on cell free RNA #liquidbiopsy #cfRNA genomebiology.biomedcentral.com/articles/10.11…

Automated evaluation of single-cell reference atlas mappings enables the identification of disease-associated cell states biorxiv.org/content/10.110… #biorxiv_bioinfo

Thrilled to see #SAVANA out in Nature Methods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…

Online Now: Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity dlvr.it/TL3Rtb

Clonal hematopoiesis (CH) in the ANZUP #TheraP study ASCO #ASCO25 presented by Asli Munzur ■ ¹⁷⁷Lu-PSMA-617: higher incidence of emergent CH compared to cabazitaxel chemotherapy ■ Most new clonal hematopoiesis mutations ¹⁷⁷Lu-PSMA-617 fall in DNA damage repair

Happy to share that our study on gut microbiome associations with colorectal cancer (CRC) is out in Nature Medicine! (doi.org/10.1038/s41591…).

Online now! Wang et al present the human universal senescence index (hUSI), a robust transcriptome-based tool that accurately predicts cellular senescence across diverse conditions, offering insights into aging and therapeutic strategies. doi.org/10.1038/s43587…

Concurrent loss of the Y chromosome in cancer and T cells impacts outcome nature.com/articles/s4158… #journals #feedly

🎉 Excited to share our new publication in Cell Reports Medicine! 🙌 Big thanks to our amazing collaborators! 📄 lnkd.in/grHHDkKB #LiquidBiopsy #Oncosomes #EVresearch #RNASeq #CancerBiology #CellReportsMedicine

(TPCPA), a proteomic resource that provides proteome-scale quantifications of 999 tumors across 22 cancer types in a unified manner, for discovering tumor biology, biomarkers, and therapeutic targets. cell.com/cancer-cell/ab…

The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs🤯 biorxiv.org/content/10.110…

Researchers have developed a DNA-based method to detect tumor-derived extracellular vesicles in blood, offering a promising step toward noninvasive cancer diagnosis. exosome-rna.com/a-dream-approa…

Preprint: Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence researchsquare.com/article/rs-678…

Nerve-to-Cancer transfer of mitochondria in primary tumors #cancer #mitochondria nature.com/articles/s4158…

scBaseCount SRA-based SRAgent #AIAgent-curated scRecounter gene annotation Largest scRNAseq database so far 230M cells 72 tissues🤠 10x Genomics only (for now) #OpenScience #ArcVirtualCellAtlas github.com/ArcInstitute/a… Nick Youngblut Hani Goodarzi Yusuf Roohani Arc Institute

Following trastuzumab deruxtecan approval, HER2 IHC 3+ testing across 65,000 solid tumors demonstrates varied prevalence. ja.ma/4elKj10

From the June issue: Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation brnw.ch/21wTOTN By Alessio Ugolini, Filippo Veglia, and colleagues. The Wistar Institute