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Cell homing and cancer metabolism can be exploited to supercharge cell therapies! Check out this beautiful new work from Jerby lab

Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy go.nature.com/42hJ1Q2

Very exciting to see the human 3D genome atlas! Congrats Jingtian Zhou

We are glad to present our exploration of aging, dietary restriction, genetics, and the microbiome, led by levlitichev, together with our collaborators The Jackson Laboratory and Calico, just published at Nature Microbiology. Major findings are the following: (1/8) nature.com/articles/s4156…

Check out this beautiful work on the next generation of spatial omics! Congrats Yodai Takei Cai Lab and colleagues

Bringing sequencing data formats into the modern age, great to see this out Noam Teyssier

🚨Preprint alert!🚨 Why do high-altitude populations have lower rates of metabolic syndrome and lower blood glucose? Superstar postdoc Yolanda tackled this❓tinyurl.com/2x7ptyn8 Gladstone Institutes Arc Institute UC San Francisco #hypoxia #oxygen

Today, we're announcing new partnerships with 10x Genomics and Ultima Genomics to accelerate development of the Arc Virtual Cell Atlas. (1/6)

1/ 🧵 THREAD: Here’s how we solved a 30-year mystery about an HIV drug. 💊 A drug used for over two decades ⚠️ Pulled from the market for cardiac risk 🤯 And no one knew why — until now We found the missing mechanism using our single-cell mosaic dataset, Tahoe-100M. Let’s talk

We're hiring! Our group Arc Institute and Stanford University has postdoc openings in 1) discovering and developing next-generation therapeutic delivery vehicles, and 2) tracking cellular dynamics. Email me if you're interested! hornslab.org

It's been a pleasure having Alishba Imran on our team as a Research Fellow! Her passion and drive made a real impact! We're always eager to collaborate with curious, motivated students—especially those excited about AI for biological discovery. Don't hesitate to reach out!

Want to discover, design, and engineer cutting-edge drug delivery vectors? We're hiring a PhD-level Scientist at the Horns Lab at Arc Institute and Stanford University! Check out bit.ly/ScientistDeliv…

Great opportunity!

This opens new frontiers in genome design, awesome work, congratulations Nicholas Perry Patrick Hsu and team!

Arc is hiring a Chief Scientific Officer! Come work with at what I think is the most dynamic and ambitious biology research organization in the world, partnering with Patrick Hsu, Silvana Konermann, Dave Burke, Arc's extraordinary faculty, and many more. We want to build the world's

We're hiring a CSO to lead our institute initiatives!

How can one efficiently simulate phylodynamics for populations with billions of individuals, as is typical in many applications, e.g., viral evolution and cancer genomics? In this work with Michael Celentano, W. DeWitt, & S. Prillo, we provide a solution. doi.org/10.1073/pnas.2… 1/n

🚨 New preprint 🚨 of our new #ML dimensionality reduction method (DR-GEM). Singular/unique things can be right in front of us, but we still won't see them. We show why this happens to unsupervised learners and how to make these learners "see" by self-supervising themselves.

Neat use of single nucleus RNA sequencing in plants to identify biosynthetic pathways

Cool! What a tour de force. Congrats Luke Koblan and team!