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Hot off the press: New paper about computational design of oligomeric proteins that can be triggered to change size and shape through allostery. Check out the beautiful thread by Arvind S Pillai !

Three ISTAustria scientists have won @erc_research Starting Grants #ERCStG! A combined 4.8 million euros will go to Marco Mondelli, Alicia K. Michael, and Lisa Bugnet. Read more about the scientists and their projects 🔗 bit.ly/3XvfQXo

#MERS vaccines built on our two-component protein nanoparticle platform induce robust neutralizing antibody responses and protect mice against vaccine-matched challenge. This collaborative project was led by Cara Chao and is out now on bioRxiv: biorxiv.org/content/10.110…

I am looking for a partner in crime who actually understands biology in Vienna — join Aithyra to make some magic oeaw.ac.at/aithyra/news/s…

Excited to join the Gene Center at LMU Gene Center Munich Universität München as a professor, looking forward to design some cool and unusual de novo proteins here!

Finally, out in Science Magazine today, our work on de novo protein design. Together with Motoyuki Hattori (服部素之) , Sergey Ovchinnikov & @hendrik_dietz we showed how we can drastically improve AF2 based hallucination, surpassing, or reaching SOTA diffusion models doi.org/10.1126/scienc…

Excited to announce our new #proteindesign strategy for allosterically controlling the kinetics of protein-protein interactions! Read on for cool applications in cytokine signaling, biosensing, and protein circuits. biorxiv.org/content/10.110…

After showing that AF2 can be used to design very large proteins by performing #RSO, I am happy to share another fun project we did: the #af2cycler Sergey Ovchinnikov @hendrik_dietz biorxiv.org/content/10.110…

“Science is a human activity.” The week before chemistry laureate David Baker visited Stockholm to receive his Nobel Prize, his 101st PhD student had just graduated from his lab. For Baker, doing great science is about collaboration – he puts great effort into fostering a

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis

Anna and Sam are X-less but they’ve done some excellent work with this project. It’s a very exciting time for enzyme designers!