1/ #ERA23 is just around the corner, but we have papers to cover! Let’s check the In Context by Luigi Cirillo, Francesca Becherucci and Martin Windpessl on NOSTONE trial. CKJ ERA - European Renal Association 🧵 by Safak Mirioglu. academic.oup.com/ckj/advance-ar…

Our new work on Clostridium Septicum superinfection complicating #HUS just released in Journal of Nephrology: rare among rare. Luigi Cirillo Università di Firenze Fondazione Meyer link.springer.com/article/10.100…

A Clinical Workflow for Cost-Saving High-Rate Diagnosis of Genetic Kidney Diseases ow.ly/ZWS250OWSzb JASN_News

Now in JASN_News. Finerenone Added to RAS/SGLT2 Blockade for Chronic Kidney Disease in Alport Syndrome. Results of a Randomized Contr… pubmed.ncbi.nlm.nih.gov/37428955/

Why we need a genomics-savvy healthcare (and public health) workforce. Via Nature Medicine nature.com/articles/s4159…

Interesting paper. May the key be the clinical interpretation of results instead of the type of test?

With CRISPR-Cas9, a repressor of fetal hemoglobin expression was disrupted in hematopoietic stem cells from three persons with sickle cell disease. Edited cells were reinfused. Hematopoiesis was restored. Read the full study results: nej.md/3L64brp

Finally out! Proud to be part of the PREDICT team!

Our editorial on #exome first strategies in medicine is out in NDT Time to change perspective Luigi Cirillo Fondazione Meyer Università di Firenze

La medicina sta andando da un’altra parte, ignorarlo è criminale

#NIPTtest (test DNA fetale), gratuito in Valle d’Aosta per le donne in gravidanza. Considerato un valido mezzo di screening, non è stato inserito nei LEA che entreranno in vigore dal 1 aprile 2024. In tutte le altre regioni è a carico delle famiglie. osservatoriomalattierare.it/news/attualita…

Our last review on kidney cancer in NDT Luigi Cirillo Samantha Innocenti

Happy to see this finally out. The first study able to define the sensitivity and specificity of commercial anti-nephrin Ab by using kidney biopsies as gold standard. Standard Elisas do the job well. kidney-international.org/article/S0085-…

Anti-slit antibodies define response to therapy and prognosis much better than histopathological lesion patterns even among patients with steroid-resistant nephrotic syndrome kidney-international.org/action/showPdf…

Look how much more important is to know if a patient is genetic or has anti-slit antibodies than if has MCD or FSGS at kidney biopsy. We have finally come to the era of autoimmune, genetic and adaptive podocytopathies. No more MCD or FSGS used as diagnosis!

Thrilled to share our latest in Kidney International Identifying anti-slit diaphragm antibodies is a game changer for patients with steroid-resistant nephrotic syndrome. Together with genetics, we can finally tailor treatments and improve outcomes. kidney-international.org/article/S0085-…

Proud to share our paper in Kidney International! Excited to see our research on anti-slit antibodies in steroid-resistant nephrotic syndrome published—a significant step toward targeted treatments. Huge thanks to my mentor Paola Romagnani and Maria Lucia Angelotti. kidney-international.org/article/S0085-…

Thinking about a genetic disease is often a good idea, even in adults. Ordering genetic testing is essential, but make sure to consult a center with adequate expertise.

Our new paper on #CKD in #solitarykidney is out in NDT. SFK is not a benign condition— patients require longlife follow up starting from childhood Special thanks to Luigi Cirillo track.smtpsendmail.com/9032119/c?p=Wa…

Now online in NDT Early identification of CKD in pts with a solitary functioning kidney 🧐There is a need for long-term follow-up protocols in congenital single kidney pts from pediatric to adult nephrology care ▶️academic.oup.com/ndt/article/do…