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1/🚨New Episode & Segment Alert🚨 Grey Matters: Because medicine is rarely black and white! Hosts: Alison Trainor, Jason Freed Discussants: Allyson Pishko, MD MSCE, Brett Carroll MD, Jeff Weinstein MD Graphic: samwoodworthmd 🎶 bit.ly/35hN1Fd ACP: bit.ly/3oVhwbI

On randomized trials (RCTs). My thoughts as an ardent proponent & having led many. 1) Easy to call for an RCT. Hard to do one. 2) For every 100 questions that an RCT is needed, we have funding for 1. 3) Designing, securing approval, & successfully completing an RCT is hard

1/ We love testing algorithms in internal medicine. 🦠 Staph Bacteremia: TTE, then (if -) ➡️ TEE 🤒Syphilis: Treponemal ➡️ RPR 💉HIT: PF4 ➡️ SRA But what happens when you get an inconclusive result?

Calling all thrombosis & #cvCoag experts. We're looking for input on draft guidance for emerging anticoagulant nomenclature. Please take 3 min to complete this survey! isth.informz.net/z/cjUucD9taT0x… ISTH World Thrombosis Day European Society of Cardiology Journals American College of Cardiology AHAMeetings Anticoagulation Forum Society for Vascular Medicine | SVM

1/16 Why are most cold agglutinins IgM? And why would any antibody adhere better at temperatures far below our own? Part of the answer is an echo of our evolutionary past. #tweetorial #medtwitter

At long last, here is part 5️⃣ in my animal #physiology in the ICU series #FOAMed Case 1: You are called about a very high blood glucose (BG) value: 738 mg/dL (41 mM)! The RN asks if you want to start an insulin drip. You say no, it’s totally normal because the patient is a: 1/

Part 6️⃣ in my extremes of animal physiology #tweetorial series: Case 1: How low can PaO2 go? You are called by the lab about an abnormal ABG result. pH 7.5 / PaCO2 20 / PaO2 22 / HCO3 15 “That’s gotta be venous” they say. “No” you reply, “Its from a ___" 1/

1/4 "Subsegmental PE" 🤔 How do you feel when you read these words in a CT report? ⁉️ How do you treat patients in these situations? 2nd year fellow Justine Ryu dug into this paper from Annals, with author @grelegal joining us for this week's #classicalhematology journal club!

1/In her 40s, my mother, an Indian American, was diagnosed with diabetes, though she was not indicated for screening This led me to ask…do we appropriately screen for diabetes by race/ethnicity? Now answered in Annals of Int Med with⭐️mentor Dhruv Kazi acpjournals.org/doi/10.7326/M2…

We are thrilled to announce that we were one of nine institutions selected by ASH for the Hematology-Focused Fellowship Training Program! We will have one new (additional) hematology-focused position in our program this year! hematology.org/education/educ…

1/13 🤔Why does multiple myeloma cause anemia and not pancytopenia? If the issue is infiltration of the bone marrow with plasma cells, wouldn't all cell lines be low? Let's have a look.

1/12 🤔Why does iron deficiency cause fatigue, even in the absence of anemia? I have often equated iron with hemoglobin and oxygen-carrying capacity. But there is so much more to it!

Excited to finally share this episode that is deeply personal for me. Thanks as always to Jason Freed the best cohost, Wendy Stead and Emmy Rubin for being discussants, samwoodworthmd for illustrations, Shreya P. Trivedi MD, MHPE for everything, and the whole editorial team! ❤️

Thank you The BMJ for the opportunity to write this med ed article. Multi-disciplinary collaboration between ID (@JeffLarnard - lead, Rodgers L Moeng MD), Heme/Onc (Jonathan Berry), Endocrine (Priyanka Majety), and a patient on a practical approach to evaluating patients w/night sweats

Here is a useful review on IV iron infusions for #irondeficiency -easy to read and can be used by patients to advocate for their care - and educate healthcare teams looking forward to us all meeting in 2 weeks to update the American guidelines. doi.org/10.1002/ajh.27…

So you want to drink blood? Here is what could happen to you 🧵

We are pleased to announce that Lisa Rosenbaum will join BIDMC Smith Center as the inaugural Writer-In-Residence, beginning July 2024. Please join us in welcoming Dr. Rosenbaum!

Come listen to me and Jason Freed get far more excited than you would think possible about tips, tricks, and strategies to optimize your workflows in Office 👇 Registration below

Guidelines are unanimous; For look risk procedures like paracentesis we need not check INR and should not give FFP Liver, gastroenterology, hematology, and interventional radiology societies agree So why the variation in managing “the cirrhotic coagulopathy”? 🧵

1/12 - Mystery #1 You are seeing a patient recently diagnosed with heart failure and started on GDMT. You notice that their hemoglobin (HGB) has increased (12 → 13 g/dL) in the intervening weeks. 🤔Which medication is the likely cause of this increase in HGB?