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Fittingly, the URL for the new AlphaFold3 server is: GOLGI.sandbox.google.com #GolgiTime *apparently it also works for proteins that do not localize to the Golgi, although we don't know why anyone would use it that way

I'm so excited to finally share the results of my PhD work! Check out this thread for all of the highlights! Ric1-Rgp1-Rab6 has been the most difficult #cryoEM project I've worked on so far, but I'm so happy with how it came together and what we learned about Rab6 activation!

Happy to share the newest preprint from Hollopeter lab Cornell University College of Veterinary Medicine: biorxiv.org/cgi/content/sh…. We propose the Inversin complex works via a dimerization mechanism. You’re probably thinking, “What the $%@! is the Inversin complex?” Let me explain:

lab alum Ryan Feathers is a DRaGoN master

Super impressive membrane-bound Arf1-AP3 cryoEM structures from the Baker lab!🤩

Final version of our latest Kramer story is out! Congrats to Hongyan Sun for leading this effort & Adnan, Dylan, Alessandro, & nicolas buchon too! Read on to learn how Wnt signaling in surprisingly many cell types promotes stem cell proliferation in the gut: sciencedirect.com/science/articl…

Big congratulations to Ryan Vignogna on his NIH F32 Postdoctoral Fellowship award!!!

New preprint. More on non-canonical motifs for DDR kinases. Here we find that Tel1 (yeast ATM) targets D/E-S/T. ... more prevalent than S/T-Q ... NOT shared with Mec1. May explain how Tel1 plays specialized roles in DNA repair and telomere maintenance. biorxiv.org/content/10.110…

Excited to announce an MBG faculty search for two assistant professor positions in collaboration with the Weill Institute for Cell and Molecular Biology, Weill Institute for Cell & Molecular Biology. Please share and apply! academicjobsonline.org/ajo/jobs/28336

Columbia will award the 2024 Louisa Gross Horwitz Prize to Scott Emr and Wesley Sundquist for discovering the ESCRT pathway and revealing how it works. Read more: columbiamed.link/47uD4jS

Awesome new paper from Francesca Bottanelli lab!

Really proud of this paper just out in JCB. At almost every turn, SURF4 surprised us. Amazing PhD student, Julija Maldutytė 🇱🇹💙💛, sleuthed it out. rupress.org/jcb/article/22…