🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

👀 An opportunity below to give input on the future of the AnVIL cloud platform - prior use/knowledge of AnVIL not required!

All models are wrong and yours are useless! In case you missed my talk yesterday on how to make clinical prediction tools useful for patients, you can read all about it here. Enjoy! doi.org/10.1038/s41698…

1/ Pleased to share our large-scale #OvarianCancer #GWAS using data from the #Ovarian #Cancer Association Consortium (#OCAC) and the Consortium of Investigators of Modifiers of #BRCA1 and #BRCA2 (#CIMBA) medrxiv.org/content/10.110… 🧵

4 years ago, we ran 16,554 GWASes for 7,271 traits across 6 ancestry groups and released the data to the public along with meta-analysis. After many careful dives through the results, we are happy to present these analyses on behalf of the Pan-UKB Project: medrxiv.org/content/10.110…

We understand that there are risks in performing this research, but believe that the benefits of inclusivity outweigh these. To mitigate risk, we wrote 17 pages of FAQs (modeled after SSGAC) to discuss social and ethical implications for a lay and scientific audience

Thrilled to see our work on genetic prediction of immune checkpoint inhibitor-mediated colitis published in Nature Communications Elad Ziv Rohit Thummalapalli Dr. Melinda Aldrich, MPH, PhD Linda Kachuri nature.com/articles/s4146…

Numbers tell a story, especially in #PublicHealth. In this NIH Intramural #SpeakingofScience episode, @NCIEpiTraining epidemiologist Dr. Meredith Shiels shares her work studying cancer mortality rates to uncover what populations might be at higher risk. go.nih.gov/R2q0490 #NPHW

Aviv Regev schooling us in dialectics (the law of the transition of quantity into quality) at the opening plenary of AACR 2024.

Have a paper marinating concerning data ethics, privacy, regulation or governance in the biosciences, or know someone who does? Please consider the BMC for a special issue I am editing on bioinformatics ethics and data privacy due 13 Dec 2024!

IGES IGES journal club recording "The All of Us Research Program: Data Resources and Access"; by Dr. Anji Musick is available here: drive.google.com/file/d/1bty6Lo…

This is a critical point. Drug target MR investigations should use genetic variants in biologically-relevant gene regions that mimic the intervention of interest. Not genetic variants that predict drug prescription or drug usage.

Grateful to Human Genetics and Genomics Advances for providing a platform for early career researchers in human genetics, to showcase their research. Try out our method: github.com/Thewhey-Brian/… Paper: cell.com/hgg-advances/f… Brian (Xinyu) Guo Nilanjan Chatterjee @NCIEpiTraining #NCI_ITEB

Genome-wide association studies in a large Korean cohort identify novel quantitative trait loci for 36 traits and illuminates their genetic architectures medrxiv.org/cgi/content/sh… #medRxiv

The Leena Peltonen Prize of 2024 goes to Sasha Gusev 🎉! I was honored to announce this and introduce Sasha just minutes ago at #ESHG24. Huge congrats!

Calling all researchers – how do you work with imputed genotype data? We need your feedback on the formats, tools and support you need, so we can improve our genetic data offering for researchers. Please complete our short survey here: ourfuturehealth.qualtrics.com/jfe/form/SV_9M…

Scarlett L. Gomez, Lauren E. McCullough, and Celeste Leigh Pearce will discuss "New Cancer Cohorts" in a plenary at the AACR Conference on The Science of Cancer Health Disparities (September 21-24, Los Angeles). bit.ly/3XXW8UW #AACRdisp24 Lauren E. McCullough DreamLab UCSF

Excited to share our new manuscript on evaluating multi-ancestry GWAS methods using large-scale simulations & real data from UK Biobank (N≈324K) & All of Us (N≈207K)! My first thesis paper under the guidance of Pete Kraft & Haoyu Zhang. Available at: medrxiv.org/content/10.110…